PHARMACY PRACTICE AND THERAPEUTICS B (METABOLIC AND ENDOCRINE)

PHA3THB

2018

Credit points: 15

Subject outline

This subject will integrate the teaching of pharmacology, medicinal chemistry and pharmacy practice relating to the use of drugs for gastroenterology, hepatic, reproductive and endocrine disorders. Students will initially explore the mechanism of action of these drugs, specifically how they affect biochemical and physiological processes at the cellular and organ level, and then relate this to the overall clinical effect on the individual. The medicinal chemistry of these drugs will then be explored so that structure-function relationships can be determined at the molecular level. Finally, the pharmacy practice issues relating to these conditions and medications will be addressed, in a manner that highlights how these drugs can ameliorate the various disease states, and affect the overall clinical condition of the patient.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorRichard Summers

Available to Study Abroad StudentsYes

Subject year levelYear Level 3 - UG

Exchange StudentsYes

Subject particulars

Subject rules

Prerequisites PHA2THA and must be admitted into the Bachelor of Pharmacy course (SHPB).

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjects PHA3PGC

Special conditionsN/A

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsGoodman & Gilman's Manual of Pharmacology and Therapeutics (Soft cover portable volume)PrescribedBrunton, L, Knollman B, & Hilal-Dandan R eds. 201310TH ED MCGRAW-HILL
ReadingsAn Introduction to Medicinal ChemistryRecommendedPatrick, G 20094TH ED, OXFORD, NEW YORK
ReadingsClinical Pharmacy and TherapeuticsRecommendedWalker R & Whittlesea C Eds 20115TH ED, EDINBURGH: CHURCHILL LIVINGSTONE
ReadingsPharmacologyRecommendedRang HP, Dale MM, Ritter JM and Moore PK 20168TH ED CHURCHILL LIVINGSTONE, EDINBURGH
ReadingsTherapeutic Guidelines: Endocrinology. Version 5RecommendedTherapeutic Guidelines Ltd. Expert Writing Group 2011THERAPEUTIC GUIDELINES LTD, MELBOURNE.
ReadingsTherapeutic Guidelines: Gastrointestinal. Version 4RecommendedTherapeutic Guidelines Ltd 2006THERAPEUTIC GUIDELINES LIMITED, MELBOURNE

Graduate capabilities & intended learning outcomes

01. Explain the pathophysiology for a selection of disease states associated with the endocrine system, reproductive system and body metabolism.

Activities:
The pathophysiology of endocrine and metabolic disease states is taught in lectures and reinforced in tutorial classes and workshops. Students apply and practice their knowledge of pathophysiology by working on case studies. Students demonstrate understanding of pathophysiology in the end-of-semester examination.

02. Relate the relevant class of drugs to activity at the molecular level, specifically, effect on relevant receptors and other regulatory molecules and processes.

Activities:
Appropriate pharmacy practice skills and judgement are taught in lectures and reinforced in tutorial classes and workshops. Students apply and practice their knowledge and skills by working on case studies during the semester and demonstrate their understanding in the end-of-semester examination.

03. Describe and explain the relationship between drug actions and therapeutic outcomes, specifically in the amelioration of disease states associated with the endocrine system or body metabolism.

Activities:
Students analyse case studies of patients with endocrine or metabolic disorders in workshops by applying their knowledge from pharmacology and pharmacy practice. Students demonstrate their understanding in the end-of-semester examination.

04. Describe the absorption, elimination and metabolism of endocrine and gastrointestinal drugs and relate this to clinical practice and how pharmacogenetics affects this.

Activities:
Therapeutic application of endocrine and gastrointestinal drugs are explained in lectures and reinforced in workshops.

05. Anticipate and rationalize interaction between drugs(including over-the-counter (OTC) and other substances)

Activities:
Drug interaction processes and their application in therapeutics including ethnic differences in human metabolism are explained in lectures and reinforced in workshops.

06. Follow guidelines to critically assess drug use and disease states in a defined case study scenario.

Activities:
Differences in human metabolism caused by altered body metabolism are taught in lectures and reinforced in tutorial classes and workshops. Students apply and practice their knowledge and skills by working on case studies during the semester and demonstrate their understanding in the end-of-semester examination.

07. Discuss alterations in human metabolism as a consequence of altered liver function.

Activities:
Case Study assignments are prepared for assessment. The aim is to integrate knowledge and skills from pharmacology, medicinal chemistry and pharmacy practice. Case studies are reinforced as questions in the final exam.

Subject options

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Start date between: and    Key dates

Bendigo, 2018, Semester 1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorRichard Summers

Class requirements

Lecture Week: 10 - 22
Three 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Tutorial Week: 13 - 22
Six 1.0 hours tutorial per study period on weekdays during the day from week 13 to week 22 and delivered via face-to-face.

WorkShop Week: 11 - 22
One 2.0 hours workshop per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.

Assessments

Assessment elementComments% ILO*
2 x case studies (1000 words equiv. in total)40 01, 02, 03, 06, 07
One 2-hour examination50 01, 02, 03, 04, 05, 06, 07
Mid-semester test (1 hour) (1000 words equiv)10 01, 02, 03, 04, 05, 06, 07