PHARMACOLOGY B

PHA2PGB

2018

Credit points: 15

Subject outline

This subject will introduce human molecular genetics and how single gene defects give rise to inherited disorders, and how these mutations may be prevented by DNA repair. Immune responses from a cellular and molecular perspective will be introduced incorporating innate immunity, inflammation, chemical cascades, adaptive immunity and cells of the immune system. The activation and expression of the genome will be introduced focusing on DNA coding and recombination; variation in human phenotype and genotype and some examples of variations in molecules of the immune system will be dealt with.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorIan Swift

Available to Study Abroad StudentsYes

Subject year levelYear Level 2 - UG

Exchange StudentsYes

Subject particulars

Subject rules

Prerequisites BIO1CO or BIO1OF

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Special conditionsN/A

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsHuman GeneticsRecommendedLewis, R 20089TH ED MCGRAW-HILL. NEW YORK.
ReadingsImmunology-A Short CoursePreliminaryCoico, R and Sunshine, G 20086TH ED, WILEY-BLACKWELL

Graduate capabilities & intended learning outcomes

01. Describe how mutations in DNA can give rise to inherited genetic disorders, and what mechanisms exist to correct these mutations.

Activities:
The origins of DNA mutations; how these lead to the development of genetic diseases, and how such mutations can be corrected will be examined in lectures and reinforced in tutorials. Understanding will be assessed in the mid-semester test and final examination.
Related graduate capabilities and elements:
Quantitative Literacy/ Numeracy
Discipline-specific GCs
Critical Thinking
Writing

02. Explain in detail the process of inflammation and the steps involved in initiation of the immune response.

Activities:
The inflammatory process and immune response initiation will be explained in lectures and reinforced in tutorials. Understanding will be assessed in the final examination.
Related graduate capabilities and elements:
Quantitative Literacy/ Numeracy
Critical Thinking
Writing
Inquiry/ Research
Discipline-specific GCs

03. Discuss how selected genetic traits are inherited in the human population and how this variation can be studied with an emphasis on multifactorial traits

Activities:
The distribution and analysis of certain genetic traits throughout the human population will be explained in lectures and reinforced in tutorials. The practical component will also examine some of these characteristics and their occurrence and distribution in the student cohort. Understanding will be assessed in the mid-semester test and final examination.
Related graduate capabilities and elements:
Writing
Critical Thinking
Quantitative Literacy/ Numeracy
Discipline-specific GCs

04. Describe how genetic variation in the human population leads to uniqueness of cells of the immune system.

Activities:
Activities: Lectures, tutorials, practical exercise. The genetic variation in several molecules of the immune recognition system will be presented in lectures. Understanding will be assessed in the final examnation.
Related graduate capabilities and elements:
Writing
Quantitative Literacy/ Numeracy
Teamwork
Discipline-specific GCs
Critical Thinking
Inquiry/ Research

05. Describe how drugs that interact with the immune system modify the immune response.

Activities:
Activities: Lectures, tutorials. Pharmacological effects on the immune system will be presented during class time. Understanding will be assessed in the final examination.
Related graduate capabilities and elements:
Writing
Discipline-specific GCs
Quantitative Literacy/ Numeracy

Subject options

Select to view your study options…

Start date between: and    Key dates

Bendigo, 2018, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorIan Swift

Class requirements

Tutorial Week: 31 - 43
One 1.0 hours tutorial per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

Lecture Week: 31 - 43
Three 1.0 hours lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

Assessments

Assessment elementComments% ILO*
2-hour written examination50 01, 02, 03, 04, 05
1-hour mid-semester test20 01, 02, 03, 04
One group review article (1500 words per student)30 01, 02, 03, 04

Singapore, 2018, Term L1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJennifer Selkirk-Bell

Class requirements

Lecture Week: 02 - 07
One 36.0 hours lecture per study period on weekdays during the day from week 02 to week 07 and delivered via face-to-face.
"36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online."

Tutorial Week: 02 - 07
One 12.0 hours tutorial per study period on weekdays during the day from week 02 to week 07 and delivered via face-to-face.
"12-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online."

Assessments

Assessment elementComments% ILO*
2-hour written examination50 01, 02, 03, 04, 05
1-hour mid-semester test20 01, 02, 03, 04
One group review article (1500 words per student)30 01, 02, 03, 04

Singapore, 2018, Term L3, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJennifer Selkirk-Bell

Class requirements

Lecture Week: 19 - 23
One 36.0 hours lecture per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
"36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online."

Tutorial Week: 19 - 23
One 12.0 hours tutorial per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
"12-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online."

Assessments

Assessment elementComments% ILO*
2-hour written examination50 01, 02, 03, 04, 05
1-hour mid-semester test20 01, 02, 03, 04
One group review article (1500 words per student)30 01, 02, 03, 04

Singapore, 2018, Term L3, Night

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJennifer Selkirk-Bell

Class requirements

Tutorial Week: 19 - 23
One 12.0 hours tutorial per study period on weekdays at night from week 19 to week 23 and delivered via face-to-face.
"12-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online."

Lecture Week: 19 - 23
One 36.0 hours lecture per study period on weekdays at night from week 19 to week 23 and delivered via face-to-face.
"36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online."

Assessments

Assessment elementComments% ILO*
2-hour written examination50 01, 02, 03, 04, 05
1-hour mid-semester test20 01, 02, 03, 04
One group review article (1500 words per student)30 01, 02, 03, 04