PHARMACEUTICAL FORMULATION B

PHA2PFB

2018

Credit points: 15

Subject outline

Pharmacists dispense many dosage forms and need to understand their strengths and limitations. Students will be taught the design and formulation of two-phase pharmaceutical products including suspensions and emulsions. Major topics include: pharmaceutically relevant physicochemical phenomena, quality assurance, preparation and extemporaneous dispensing of pharmaceutical preparations, including pharmaceutical calculations.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorChristina Dennis

Available to Study Abroad StudentsNo

Subject year levelYear Level 2 - UG

Exchange StudentsNo

Subject particulars

Subject rules

Prerequisites Must be admitted in SHPB and have passed PHA1PFA.

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Special conditions A satisfactory placement, report and/or manual is required to pass this subject. Students must have a current Police check and Working with Children check before attending placement.

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsAulton's Pharmaceutics: the design and manufacture of MedicinesPrescribedAulton, ME and Taylor, K. 20134TH ED., LONDON: CHURCHILL LIVINGSTONE
ReadingsAustralian Pharmaceutical Formulary and HandbookPrescribedSansom, L (ed), 201523rd ED., CANBERRA: PHARMACEUTICAL
ReadingsMartindale: the complete drug referenceRecommendedBrayfield, A (ed). 201438TH ED., 2014 LONDON: PHARMACEUTICAL PRESS
ReadingsPharmaceutical PracticeRecommendedRees JA, Smith, I. and Watson J 20145TH ED., LONDON: CHURCHILL LIVINGSTONE
ReadingsPhysicochemical Principles of PharmacyRecommendedFlorence, AT& Attwood, D 20115TH ED., BASINGSTOKE: MACMILLAN
ReadingsExtemporaneous Dispensing Record SheetsPrescribedLa Trobe University 2018Available from the bookshop

Graduate capabilities & intended learning outcomes

01. Meet the Pharmaceutical Society of Australia (PSA) Professional Practice Standard for Compounding by preparing and dispensing 2-phase products and complex solutions.

Activities:
Activity: tutorials, practical work. Assessment: Assessed in the in-class practical test, practical skills assessment, including exam. Students must prepare and dispense solution and two-phase formulations. Marks are awarded for labelling and documentation accuracy, elegance of product. Quality assurance protocols are used throughout, and students must be able to self-assess the quality of their products.

02. Explain and predict the properties of 2-phase systems and discuss their formulation.

Activities:
Activity: Lectures, tutorials, practical work. Assessment: Assessed in the in-class practical test, practical skills assessment, which may include an oral component, written exam. In these assessments students are asked to select an appropriate topical product for an application and justify this choice.

03. Use knowledge of topical formulations to justify the selection of an appropriate topical product for a specified use.

Activities:
Activity: Lectures, tutorials, practical work. Assessment: Assessed in the in-class practical test, practical skills assessment, which includes an oral component, written exam. In these assessments students are asked to select an appropriate topical product for an application and justify this choice.

04. Accurately perform pharmaceutical calculations.

Activities:
Activity: Lectures, tutorials, on-line quiz bank. Assessment: Students should successfully complete the on-line quizzes where they must achieve a score of 90% on quiz 3 to sit the calculation test. They must achieve 90% on quiz 3 to pass the subject. The question bank is accessible via the LMS - students can repeat quizzes as often as they like. A Question and Answer forum is set up to encourage collaborative problem-solving. There is also a dedicated tutorial for calculations and problem-solving. There are also calculation questions on the written exam, and skills in calculations are required in the practical assessment.

05. Discuss the choice of packaging and application of quality assurance to compounded products.

Activities:
Activity: Lectures, tutorials. Assessment: Written exam.

06. Discuss the mechanisms in place to ensure professional efficient running of a pharmacy department.

Activities:
Activity: Placement

Subject options

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Start date between: and    Key dates

Bendigo, 2018, Semester 1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorChristina Dennis

Class requirements

Tutorial Week: 10 - 22
Two 1.0 hours tutorial per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Practical Week: 10 - 22
Seven 3.0 hours practical per study period on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Placement - Off Site
One 5.0 days placement - off site per study period on weekdays during the day and delivered via face-to-face.
"one 1-week placement (during the mid year break)"

Lecture Week: 10 - 22
Two 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Assessments

Assessment elementComments% ILO*
2 hour examination (2,000-word equivalent)50 02, 01, 03, 05, 04
Calculation competency test (equivalent to 800-words)Students undertake 3 on-line quizzes with immediate feedback Must achieve 90% on each quiz to open the next quiz including quiz 3 to sit this Calculations Competency test.25 04
In-class practical test (equivalent to 1,000-words)Students who fail to complete at least 1 competent product are required to repeat product to competency under guidance. Hurdle requirement at least one competent product produced.25 03, 01
Placement taskHurdle requirement 06