MOLECULAR GENETICS AND GENOMICS

GEN3MGG

2018

Credit points: 15

Subject outline

Molecular Genetics and Genomics introduces students to advanced concepts in modern molecular genetics and genomics. The topics covered in this subject include the genetic regulation of normal development and genetic disease; stem cells and regenerative medicine; Cancer and molecular medicine; Model organisms for modelling Human genetic diseases, including Mice and fruit fly; Immuno-genetics; Forensic genetics; Genomics, bioinformatics and gene therapy. A large part of this blended subject involves problem based learning, where students work through online Genetics case studies, bioinformatics projects and scientific literature analyses, which provide the conceptual basis for face to face workshops.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorAdam Hart

Available to Study Abroad StudentsYes

Subject year levelYear Level 3 - UG

Exchange StudentsYes

Subject particulars

Subject rules

Prerequisites GEN2MHG

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Special conditionsN/A

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsGenetics Analysis and PrinciplesRecommendedBrooker, RMCGRAW HILL 2011
ReadingsHuman Embryology and developmentalRecommendedCarlson, BELSEVIER 2013
ReadingsHuman Evolutionary GeneticsRecommendedJobling M.A, Hurles. M and Tyler-Smith CGARLAND SCIENCE 2004
ReadingsHuman Molecular Genetics 4th EditionRecommendedStrachan, T and Read, A.P.GARLAND SCIENCE 2011
ReadingsPrinciple of DevelopmentRecommendedWolpert, L and Tickle COXFORD 2010
ReadingsJaneway's Immunobiology 7th editionRecommendedMurphy, Travers and WalportGarland Science
ReadingsConcepts of Genetics, 10th, international editionRecommendedKlug et. al.,Pearson

Graduate capabilities & intended learning outcomes

01. Analyse and evaluate experimental and published data relating to molecular genetics experiments to prepare a comprehensive literature review.

Activities:
A research topic related to the subject intended learning outcomes will be selected by the student. Online training in evidence based research review writing will be provided online and workshopped. Students will also receive online training in the use of referencing software and receive a round of written feedback before submitting a 500 word literature review via turnitin.
Related graduate capabilities and elements:
Literacies and Communication Skills
Literacies and Communication Skills
Inquiry and Analytical Skills
Inquiry and Analytical Skills
Personal and Professional Skills
Discipline -Specific Knowledge and Skills

02. Articulate and apply advanced genetics theory and analytical methods in the genetic control of development, the structure and function of genes and chromosomes, human variation, genetic disease and genome biology.

Activities:
Genetics concepts and analytical methods are explained in lectures and recommended reading. Students participate in theory revision sessions. Students can revise content and practice their knowledge via online resources (LMS quizzes Peerwise) including: practice exam questions, discussion groups, lectopia and other materials. Students attempt 2 in- class multiple choice exams and can use the feedback on these exams to structure their revision before the end-of- semester examination (2 x 1.5 hour theory exam)
Related graduate capabilities and elements:
Inquiry and Analytical Skills
Inquiry and Analytical Skills
Discipline -Specific Knowledge and Skills

03. Use bioinformatics to solve genetics problems.

Activities:
Information to complete assignments will be available online. Individually, students will access online worksheets, tutorials, genome databases and bioinformatics tools to solve genetics problems: - Students have to complete bioinformatics worksheets using online tutorials and database mining tools. - Students perform DNA sequence analysis online to identify disease related DNA polymorphisms and to design molecular clinical diagnostic tests- Students use online databases and apply gene search and analysis tools to analyse clinical case study data.
Related graduate capabilities and elements:
Literacies and Communication Skills
Inquiry and Analytical Skills
Inquiry and Analytical Skills
Inquiry and Analytical Skills
Personal and Professional Skills
Discipline -Specific Knowledge and Skills

04. Apply clinical problem solving skills to diagnose genetic diseases.

Activities:
An online problem solving clinical case study activity is followed by a formative learning quiz. Study questions and student online feedback arising from the online case study is then discussed in a workshop. An assessed quiz is then taken online to test knowledge. Six case studies will be conducted and students will select one to create a case study poster that is also assessed. Written feedback on the posters is given by peers and academics.
Related graduate capabilities and elements:
Literacies and Communication Skills
Literacies and Communication Skills
Literacies and Communication Skills
Inquiry and Analytical Skills
Inquiry and Analytical Skills
Inquiry and Analytical Skills
Personal and Professional Skills
Personal and Professional Skills
Personal and Professional Skills
Discipline -Specific Knowledge and Skills

Subject options

Select to view your study options…

Start date between: and    Key dates

Melbourne, 2018, Semester 1, Blended

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorAdam Hart

Class requirements

Unscheduled Online Class Week: 10 - 22
One 2.0 hours unscheduled online class per week on weekdays during the day from week 10 to week 22 and delivered via blended.
"Online Lectorial and knowledge test quiz followed by online activity and assessment"

Lecture/Workshop Week: 10 - 22
One 2.0 hours lecture/workshop per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"Lecture and knowledge test quiz followed by problem based workshop and assessment."

Assessments

Assessment elementComments% ILO*
Weekly online activity and quiz (900 words equivalent)20 02
Case study online quizzes & case study poster (600 words equivalent)14 01, 02, 04
Literature review and bioinformatics worksheets (1000 words)26 01, 02, 03, 04
One 2-hour exam at end of semester (1800 words equivalent)40 02