Dr Kaye N. Truscott

Senior Research Fellow, Lab Head

College of Science, Health and Engineering
School of Molecular Sciences
Department of Biochemistry and Genetics
La Trobe Institute for Molecular Science

LIMS1 level 4, Office - Rm418; Lab - Rm405, Melbourne (Bundoora)


BSc, DipEd, PhD. La Trobe

Membership of professional associations

Australian Society for Biochemistry and Molecular Biology

Area of study

Biochemistry and Molecular Biology

Brief profile

For her doctorate, Kaye studied molecular chaperone assisted protein folding in thermophilic bacteria under the supervision of Prof. Robert Scopes. In 1999, shortly after obtaining her PhD, she was awarded an Alexander von Humboldt Research Fellowship to examine the protein import machinery in mitochondria of yeast and was hosted by Prof. Nikolaus Pfanner (Institute for Biochemistry and Molecular Biology, Freiburg, Germany). In 2001 Kaye was promoted to group leader within the Pfanner lab where she continued her studies on the molecular mechanisms of mitochondrial protein translocation. In 2004 she was awarded a QEII Fellowship by the Australian Research Council to study protein degradation by AAA+ proteases in bacteria and mitochondria. In 2009 Kaye was awarded an ARC Future Fellowship to extend her research in the area of mitochondrial protein homeostasis focusing on the role of AAA+ proteases in protein quality control and the mitochondrial unfolded protein response. Kaye is currently a Senior Research Fellow and is examining mitochondrial protein biogenesis pathways and protein homeostasis networks in relation to human health and disease. Kaye contributes to undergraduate lecturing and also post-graduate training through the supervision of practical classes and higher degree research students.

Research interests

Mitochondria biogenesis and disease

- Respiratory complex II assembly, Mitochondrial processing & quality control proteases

Neurodegenerative diseases

- Neurodegenerative diseases associated with mitochondrial protein dysfunction

Teaching units

Recent publications

·       Book Chapters

·       Journals 

Previewed by M. Mayer in Nat. Struct. & Mol. Biol. (2004), 11, 6-8.

Rated highly by Faculty 1000 and previewed in Nat. Rev. Mol. Cell Biol. (2003) 4, 343.

Rated highly by Faculty of 1000 and previewed in Nat. Rev. Mol. Cell Biol. (2003) 4, 5.

Previewed in Nat. Struct. Biol. (2004) 8, 1008-1010.

Research projects

Please contact Dr Kaye Truscott directly.