Research Fellow
Faculty of Science, Technology and Engineering
School of Psychological ScienceGeorge Singer Building, room 415, Melbourne (Bundoora)
BA, BSc(Hons), DPsych (Clin Neuro)
Australian Psychological Society (APS); APS College of Clinical Neuropsychologists (CCN)
Psychology
Dr Pike is a registered Clinical Neuropsychologist based in the School of Psychological Science. She holds an NHMRC post doctoral clinical training fellowship. Her research interests include cognitive interventions, especially involving memory. Her current research focuses on intervention with older adults, including people with subjective memory complaints, mild cognitive impairment, Alzheimer's disease and other dementias, as well as those who are ageing normally. She is also interested in the development of sensitive neuropsychological assessment tasks that can detect the subtle, early cognitive changes associated with prodromal Alzheimer's disease, as well as assessments that have everyday relevance (such as those set in a naturalistic setting).
- Cognitive intervention, subjective memory complaint, mild cognitive impairment, Alzheimer's disease
Papers in refereed journals
1. Pike KE, Kinsella GJ, Ong B, Mullaly E, Rand E, Storey E, Ames D, Saling M, Clare L, Parsons S. (2012). Names and Numberplates: Quasi-everyday associative memory tasks for distinguishing amnestic mild cognitive impairment from healthy ageing Journal of Clinical and Experimental Neuropsychology, 34 (3), 269 - 278.
2. Delprado J, Kinsella G, Ong B, Pike K, Ames D, Storey E, Saling M, Clare L, Mullaly E, Rand E. Clinical Measures of Prospective Memory in Amnestic Mild Cognitive Impairment. (2012). Journal of the International Neuropsychological Society, 18, 295 - 304.
3. Hutchens RL, Kinsella GJ, Ong B, Pike KE, Parsons S, Storey E, Ames D, Saling,MM, Mullaly E, Rand E, & Clare L. (2011, in press). Knowledge and use of memory strategies in amnestic mild cognitive impairment. Psychology and Aging.
4. Chételat G, Villemagne VL, Pike KE, Ellis KA, Ames DA, Masters CL, Rowe CC, the Australian Imaging Biomarkers and Lifestyle Study of ageing (AIBL) Research Group. (2012). Relationship between memory performance and beta-amyloid deposition at different stages of Alzheimer’s disease. Neurodegenerative Diseases, 10, 141-144.
5. Leyton CE, Villemagne VL, Savage S, Pike KE, Ballard K, Piguet O, Burrell J, Rowe CC, Hodges JR. (2011). Subtypes of Progressive Aphasia: application of the International Consensus Criteria and validation using β-amyloid imaging. Brain, 134(10), 3030 - 3043.
6. Villemagne, VL, Pike KE, Chetelat G, Ellis KE, Mulligan RS, Bourgeat P, Ackermann U, Jones G, Szoeke C, Salvado O, Martins R, O’Keefe G, Mathis CA, Klunk WE, Ames D, Masters CL, & Rowe CC. (2011). Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease. Annals of Neurology, 69, 181 - 192.
7. Chételat G, Villemagne VL, Pike KE, Ellis KA, Bourgeat P, Jones G, O’Keefe, GJ, Salvado O, Szoeke C, Martins RN, Ames D, Masters CL, Rowe CC, the Australian Imaging Biomarkers and Lifestyle Study of ageing (AIBL) research group. (2011). Independent contribution of temporal β-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer’s disease. Brain,134, 798 - 807.
8. Watt, AD, Perez KA, Faux NG, Pike KE, Rowe CC, Bourgeat P, Salvado O, Masters CL, Villemagne VL, & Barnham KJ. (2011). Increasing the predictive accuracy of amyloid-β blood-borne biomarkers in Alzheimer’s disease. Journal of Alzheimer's Disease, 24(1), 47 - 59.
9. Pike KE, Ellis KA, Villemagne VL, Good N, Chételat G, Ames D, Szoeke C, Laws S, Verdile G, Martins R, Masters CL, Rowe CC (2011). Cognition and beta-amyloid in preclinical Alzheimer's disease: Data from the AIBL study. Neuropsychologia, 49, 2384 - 2390.
10. Chételat G, Villemagne VL, Bourgeat P, Pike KE, Jones G, Ames D, Ellis KA, Szoeke C, Martins RN, O'Keefe G, Salvado O, Masters CL, Rowe CC, the AIBL research group. (2010). Relationship between atrophy and β-amyloid deposition in Alzheimer disease. Annals of Neurology, 67, 317 - 324.
11. Kinsella G, Mullaly E, Pike, K. (2010). Cognitive interventions in early Alzheimer’s disease and mild cognitive impairment InPsych: The Bulletin of the Australian Psychological Society, 14 - 15.
12. Bahar-Fuchs A, Chetelat G, Villemagne VL, Moss S, Pike KE, Masters CL, RoweC & Savage G. (2010). Olfactory deficits and amyloid-beta burden in Alzheimer’s disease, mild cognitive impairment, and healthy aging: A PiB PET study. Journal of Alzheimer’s Disease, 22 (4),1081 - 1087.
13. Chételat G, Villemagne VL, Pike KE, Baron J, Bourgeat P, Jones G, Faux NG, Ellis KA, Salvado O, Szoeke C, Martins RN, Ames D, Masters CL, Rowe CC, the AIBL research group. (2010). Larger temporal volume in asymptomatic elderly with high versus low beta-amyloid deposition. Brain, 133, 3349 - 3358.
14. Villemagne VL, Perez K, Pike K, Kok W, Rowe C, White A, Bourgeat P, Salvado O, Bedo J, Hutton C, Faux N, Masters C, Barnham K. (2010). Blood borne Aβ dimer correlates with clinical markers of Alzheimer's disease. Journal of Neuroscience, 30(18), 6315 - 6322.
15. Bourgeat P, Chételat G, Villemagne VL, Fripp J, Raniga P, Pike K, Acosta O, Szoeke C, Ourselin S, Ames D, Ellis KA, Martins RN, Masters CL, Rowe CC, Salvado O. (2010). Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia. Neurology, 74, 121 - 127.
16. Rowe CC, Ellis KA, Rimajova M, Bourgeat P, Pike KE, Jones G, Fripp J, Tochon-Danguy H, Morandeau L, O'Keefe G, Price R, Raniga P, Robins P, Acosta O, Lenzo N, Szoeke C, Salvado O, Head R, Martins R, Masters CL, Ames D, Villemagne VL. (2010). Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiology of Aging, 31, 1275 - 1283.
17. Villemagne VL, Pike K, Pejoska S, Boyd A, Power M, Jones G, Masters CL, Rowe CC. (2010). 11C-PiB PET ABri imaging in Worster-Drought syndrome (Familial British dementia): a case report. Journal of Alzheimer's Disease, 19(2), 423 - 428.
18. Ellis KA, Bush AI, Darby D, De Fazio D, Foster J, Hudson P, Lautenschlager NT, Lenzo N, Martins RN, Maruff P, Masters C, Milner A, Pike K, Rowe C, Savage G, Szoeke C, Taddei K, Villemagne V, Woodward M, Ames D, the AIBL research group. (2009). The Australian Imaging, Biomarkers and Lifestyle Study of ageing (AIBL): methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease. International Psychogeriatrics, 21(4), 672 - 687.
19. Fodero-Tavoletti MT, Cappai R, McLean CA, Pike KE, Adlard PA, Cowie T, Connor AR, Masters CL, Rowe CC, Villemagne VL. (2009). Amyloid imaging in Alzheimer's disease and other dementias. Brain Imaging and Behavior, 3, 246 - 261.
20. Villemagne, V.L., Fodero-Tavoletti M.T., Pike, K.E., Cappai, R., Masters C.L., & Rowe, C.C. (2008). The ART of Loss: Aβ imaging in the evaluation of Alzheimer's disease and other dementias. Molecular Neurobiology, 38(1), 1 - 15.
21. Pike, KE, Rowe CC, Moss SA, & Savage G. (2008). Memory profiling with paired associate learning in Alzheimer’s disease, mild cognitive impairment, and healthy aging. Neuropsychology, 22(6), 718 - 728.
22. Pike, KE & Savage G. (2008). Memory profiling in mild cognitive impairment: Can we determine risk for Alzheimer’s disease? Journal of Neuropsychology, 2(2), 361 - 372.
23. Rowe, CC, Ackermann U, Browne W, Mulligan R, Pike KE, O’Keefe G, Tochon-Danguy H, Chan G, Berlangieri SU, Jones G, Dickinson-Rowe K, Kung HP, Zhang W, Kung MP, Skovronsky D, Dyrks T, Holl G, Krause S, Friebe M, Lehman L, Lindemann S, Dinkelborg LM, Masters CL, Villemagne VL. (2008). Imaging of amyloid β in Alzheimer’s disease with 18F- BAY94-9172, a novel PET tracer: proof of mechanism. Lancet Neurology, 7, 129 - 135.
24. Villemagne VL, Pike KE, Darby D, Maruff P, Savage G, Ng S, Ackermann U, Cowie TF, Currie J, Chan SG, Jones G, Tochon-Danguy H, O’Keefe G, Masters CL, Rowe CC. (2008). Aβ deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease. Neuropsychologia, 46(6),1688 - 1697.
25. Fripp J, Bourgeat P, Acosta O, Raniga P, Modat M, Pike KE, Jones G, O’Keefe G, Masters CL, Ames D, Ellis KA, Maruff P, Currie J, Villemagne VL, Rowe CC, Salvado O, Ourselin S. (2008). Appearance modeling of 11C PiB PET images: Characterizing amyloid deposition in Alzheimer’s disease, mild cognitive impairment and healthy aging. Neuroimage, 43, 430 - 439.
26. Pike, K, Savage G, Villemagne VL, Ng S, Moss SA, Maruff P, Mathis CA, Klunk WE, Masters CL & Rowe CC. (2007). β-amyloid imaging and memory in nondemented individuals: Evidence for preclinical Alzheimer’s disease. Brain, 130, 2837 - 2844.
27. Rowe CC, Ng S, Ackermann U, Gong SJ, Pike K, Savage G, Cowie TF, Dickinson KL, Maruff P, Darby D, Smith C, Woodward M, Merory J, Tochon-Danguy H, O'Keefe G, Klunk WE, Mathis CA, Price JC, Masters CL, Villemagne VL. (2007). Imaging β-amyloid burden in aging and dementia. Neurology, 68, 1718 - 1725.