Professor Anne E

Professor Anne E Holland


College of Science, Health and Engineering

School of Allied Health

Department of Rehabilitation, Nutrition and Sport

Alfred Health Clinical School,


BAppSc, PhD


PhD researcher

Area of study


Brief profile

Anne Holland leads a research program that aims to optimise health and wellbeing for people with cardiorespiratory disease, based at the Alfred Health Clinical School. Anne’s research is investigating new models for pulmonary rehabilitation, including low cost home-based models and telerehabilitation, as well as defining the benefits of pulmonary rehabilitation in new populations such as interstitial lung disease. She has over 180 publications in peer reviewed journals related to chronic respiratory disease and rehabilitation. Her publications have been cited over 4700 times, including in 13 national and international treatment guidelines. Anne has received over $AUD 11 million in competitive research funding since 2003.

Anne's role is to lead and grow the physiotherapy clinical research program at Alfred Health, where she provides supervision and mentoring to clinicians and research students undertaking research projects in a clinical setting.

Research interests

Chronic disease

- Chronic respiratory disease


- Pulmonary rehabilitation

Recent publications

Alison JA, McKeough ZJ, Johnston K, McNamara RJ, Spencer LM, Jenkins SC, Hill CJ, McDonald VM, Frith P, Cafarella P, Brooke M, Cameron-Tucker HL, Candy S, Cecins N, Chan ASL, Dale M, Dowman LM, Granger C, Halloran S, Jung P, Lee A, Leung R, Matulick T, Osadnik C, Roberts M, Walsh J, Wootton S, Holland AE. Australian and New Zealand Pulmonary Rehabilitation Guidelines. Respirology 2017; 22 (4):800–819

Cox NS, Oliveria CC, Lahham A, Holland AE. Pulmonary rehabilitation referral and participation are commonly influenced by environment, knowledge and beliefs about consequences: a systematic review using the Theoretical Domains Framework. Journal of Physiotherapy 2017, 63 (2): 84–93.

Khor YH, Goh NSL, McDonald CF, Holland AE. Oxygen Therapy for Interstitial Lung Disease: A Mismatch Between Patient Expectations and Experiences. Annals of the American Thoracic Society, published online 7th March 2017,

Dowman LM, McDonald CF, Hill CJ, Lee AL, Barker K, Boote C, Glaspole I, Goh NSL, Southcott AM, Burge AT, Gillies R, Martin A, Holland AE. The evidence of benefits of exercise training in interstitial lung disease: a randomized controlled trial. Thorax 2017;72: 610–619.

Dowman LM, McDonald CF, Bozinovski S, Vlahos R, Gillies R, Pouniotis D, Hill CJ, Goh NSL, Holland AE. Greater endurance capacity and improved dyspnoea with acute oxygen supplementation in idiopathic pulmonary fibrosis patients without resting hypoxemia. Respirology 2017; 22 (5): 957–964.

Morris N, Kermeen F, Holland AE. Exercise based rehabilitation programs for pulmonary hypertension (review). Cochrane Database of Systematic Reviews 2017; CD011285. doi: 10.1002/14651858.CD011285.pub2.

Ward N, Stiller K, Rowe H, Holland AE. The psychometric properties of the Leicester Cough Questionnaire and Respiratory Symptoms in CF tool in cystic fibrosis: A preliminary study. Journal of Cystic Fibrosis; published online December 13th 2016, doi: 10.1016/j.jcf.2016.11.011.

Hoaas H, Morseth B, Holland AE, Zanaboni P. Are Physical Activity and Benefits Maintained After Long-Term Telerehabilitation in COPD? International Journal of Telerehabilitation 2016; 8(2); 39-48.

McDonald VM, Wood LG, Holland AE, Gibson PG. Obesity in COPD: to treat or not to treat? Expert Review of Respiratory Medicine. 2016; 10:1-3. doi: 10.1080/17476348.2017.1267570.

Schulz P, Prescott J, Shifman J, Fiore J Jr, Holland A, Harding P. Comparing patient outcomes for care delivered by advanced musculoskeletal physiotherapists with other health professionals in the emergency department-A pilot study. Australas Emerg Nurs J. 2016 Nov;19(4):198-202. doi: 10.1016/j.aenj.2016.06.001.

Slade SC, Dionne CE, Underwood M, Buchbinder R, Beck B, Bennell K, Brosseau L, Costa L, Cramp F, Cup E, Feehan L, Ferreira M, Forbes S, Glasziou P, Habets B, Harris S, Hay-Smith J, Hillier S, Hinman R, Holland A, Hondras M, Kelly G, Kent P, Lauret GJ, Long A, Maher C, Morso L, Osteras N, Peterson T, Quinlivan R, Rees K, Regnaux JP, Rietberg M, Saunders D, Skoetz N, Sogaard K, Takken T, van Tulder M, Voet N, Ward L, White C. Consensus on Exercise Reporting Template (CERT): Modified Delphi Study. Phys Ther. 2016 Oct;96(10):1514-1524

Bell EC, Cox NS, Goh N, Glaspole I, Westall G, Watson A, Holland AE. Oxygen therapy for interstitial lung disease: a systematic review. European Respiratory Review, In Press, accepted 20th November 2016.

Hodgson C, Goligher EC, Young ME, Keating JL, Holland AE, Romero L, Bradley SJ, Tuxen D. Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation. Cochrane Database of Systematic Reviews 2016, Issue 11. Art. No.: CD006667. DOI: 10.1002/14651858.CD006667.pub3

Schulz P, Prescott J, Shifman J, Fiore J, Holland A, Harding P. Comparing patient outcomes for care delivered by advanced musculoskeletal physiotherapists with other health professionals in the emergency department ‐ A pilot study. Australasian Emergency Nursing Journal. 2016;19(4):pp198‐202.

Crouch R, Kulkarni HS, Holland A, Lareau S, Sockrider M. Pulmonary exercise training before and after lung transplantation. American Journal of Respiratory and Critical Care Medicine 2016;194(5): 9-10.

Lahham A, McDonald CF, Holland AE. Exercise training alone or with the addition of activity counselling improves physical activity levels in chronic obstructive pulmonary disease (COPD) – A systematic review and meta-analysis of randomized controlled trials. International Journal of Chronic Obstructive Pulmonary Disease 2016; 3121-3136. doi: 10.2147/COPD.S121263.

Tipping CJ, Harrold M, Holland AE, Romero L, Nisbet T, Hodgson CL. Systematic review of the effects of active mobilization and rehabilitation in ICU on mortality and function. Intensive Care Medicine, In Press, published online 18th November 2016. doi: 10.1007/s00134-016-4612-0.

Howard ME, Piper AJ, Stevens B, Holland AE, Yee BJ, Dabscheck E, Mortimer D, Burge AT, Flunt D, Buchan C, Rautela L, Sheers N, Hillman D, Berlowitz DJ. A randomised controlled trial of CPAP vs non-invasive ventilation for initial treatment of obesity hypoventilation syndrome. Thorax, In Press, published online 15th November 2016. doi: 10.1136/thoraxjnl‐2016‐208559.

Strookappe B, Saketkoo LA, Elfferich M, Holland A, De Vries J, Knevel T, Drent M. Physical activity and training in sarcoidosis: review and experience-based recommendations. Expert Review of Respiratory Medicine 2016; 10(10): 1057-68. doi: 10.1080/17476348.2016.1227244.

Raymond MJ, Jeffs KJ, Winter A, Soh S, Hunter P, Holland AE. The effects of a high intensity functional exercise group on clinical outcomes in hospitalized older adults: An assessor-blinded randomized controlled trial. Age and Ageing, In Press, published online 7th December 2016. doi: 10.1093/ageing/afw215.

Fuller LM, Button B, Tarrant B, Steward R, Bennett L, Snell G, Holland AE. Longer versus shorter supervised rehabilitation following lung transplantation: A randomised trial. Archives of Physical Medicine and Rehabilitation, In Press, published online 30th September 2016. doi: 10.1016/j.apmr.2016.09.113

Holland AE, Harrison S, Brooks D. Multimorbidity, frailty and COPD: are the challenges for pulmonary rehabilitation in the name? Chronic Respiratory Disease 2016; 3(4):pp372‐382.

Holland AE, Mahal A, Hill CJ, Lee AL, Burge AT, Cox NS, Moore R, Nicolson C, O'Halloran P, Lahham A, Gillies R, McDonald CF. Home-based rehabilitation for chronic obstructive pulmonary disease using minimal resources: a randomised, controlled equivalence trial. Thorax 2017;72:57-65,

Zanaboni P, Dinesen B, Hjalmarsen A, Hoaas H, Holland AE, Oliveira CC, Wootton R. Long term integrated telerehabilitation of COPD patients. A multi-center randomized controlled trial (iTrain). BMC Pulmonary Medicine 2016; 16(1) art. no. 126.

Hayes K, Holland AE, Pellegrino VA, Leet AS, Fuller LM, Hodgson CL. Physical function after extracorporeal membrane oxygenation in patients pre or post heart transplantation – an observational study. Heart and Lung 2016; 45(6):525‐531. doi: 10.1016/j.hrtlng.2016.07.007.

Passey S, Hansen M, Bozinovski S, McDonald CF, Holland AE, Vlahos R. Emerging therapies for the treatment of skeletal muscle wasting in chronic obstructive pulmonary disease. Pharmacology and Therapeutics 2016 Oct; 166:56-70. doi: 10.1016/j.pharmthera.2016.06.013.

Kimmel L, Liew S, Sayer J, Newnham H, Holland AE. HIP4Hips: High Intensity Physiotherapy for Hip fractures in the Acute Hospital Setting decreases hospital length of stay – a randomised controlled trial. Medical Journal of Australia 2016; 205(2):73-78. doi: 10.5694/mja16.00091.

Lee AL, Hill CJ, McDonald CF, Holland AE. Pulmonary rehabilitation in individuals with non-cystic fibrosis bronchiectasis: a systematic review. Archives of Physical Medicine and Rehabilitation, In Press, published online June 16th 2016. doi: 10.1016/j.apmr.2016.05.017.