Staff profile

Dr Suresh Mathivanan

NH&MRC Biomedical Research Fellow, LIMS Fellow

Faculty of Science, Technology and Engineering

School of Molecular Sciences
Department of Biochemistry
La Trobe Institute for Molecular Science

PS4 Building, Melbourne (Bundoora)

 

Qualifications

PhD

Area of study

Biochemistry and Molecular Biology
Biomedical Science
Biotechnology

Brief profile

Suresh undertook a PhD in proteomics and bioinformatics at the Johns Hopkins University, USA and Institute of Bioinformatics, India.  In 2008, Suresh joined Ludwig Institute for Cancer Research, Melbourne, Australia as a postdoctoral researcher.

In 2011, he received a NH&MRC Peter Doherty fellowship to study exosomes secreted by cancer cells. 

His research impact can be highlighted by a H-index of 16 and average citation of 85 times (as of July 2012). 

Suresh moved to the Department of Biochemistry, La Trobe Institute for Molecular Science (LIMS) at La Trobe University after receiving a LIMS fellowship to set up his own research group in 2011.

At LIMS, Mathivanan's laboratory is focused on exosomes, their role in cancer and intercellular communication.

Research interests

Exosomes, secretome and systems biology

- Please contact me to discuss a topic.

Recent publications

 

 

Mathivanan, S., Ji, H., Tauro, B.J., Chen, Y.S. and Simpson, R.J. (2012). Identifying mutated proteins secreted by colon cancer cell lines using mass spectrometry. Journal of Proteomics. In press.

 

Simpson, R.J.#, Kalra, H. and Mathivanan, S.# (2012). ExoCarta as a resource for exosomal research. Journal of Extracellular Vesicles. 1: 18374. # co-corresponding author 

 

Simpson, R.J. and Mathivanan, S.# (2012). Extracellular Microvesicles: The Need for Internationally Recognised Nomenclature and Stringent Purification Criteria. Journal of Proteomics and Bioinformatics. 5, ii. # corresponding author

 

Mathivanan, S.#, Patterson, C., Reid, G. and Simpson, R.J.# (2012). ExoCarta for exosomal RNA, proteins and lipids. Nucleic Acids Research. D1241-4. # co-corresponding author

 

Tauro, B.J., Greening, D.W., Mathias, R.A., Ji, H., Mathivavan, S., Scott, A.M., Simpson, R.J. (2012).Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Methods. In press.

 

Chen, Y., Mathias, R.A., Mathivanan, S., Kapp, E.A., Moritz, R.L., Zhu, H. and Simpson, R.J. (2011). Proteomic profiling of MDCK plasma membranes reveals Wnt-5a involvement during oncogenic H-Ras/TGF-β-mediated epithelial-mesenchymal transition. Mol Cell Proteomics. 10, M110.001131. 

 

Mathivanan, S., Hong, J. and Simpson, R.J. (2010). Exosomes: extracellular organelles important in intercellular communication. J Proteomics. 10, 1907-20.

 

Mathivanan, S., Lim, J. W. E., Taro, B., Hong, J., Moritz, R. L. and Simpson, R. J. (2010). Proteomic analysis of A33-immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature. Mol Cell Proteomics. 2, 197-208.

 

Mathivanan, S. and Simpson, R. J. (2009). ExoCarta: A compendium of exosomal proteins and RNA. Proteomics. 9, 4997-5000.

 

Simpson, R. J., Lim, J. W. E., Moritz, R. L. and Mathivanan, S. (2009). Exosomes: proteomic insights and diagnostic potential. Expert reviews in proteomics. 6, 267-83.

 

Harsha, H. C., Kandasamy, K., Ranganathan, P., Rani, S., Ramabadran, S., Gollapudi, S., Balakrishnan, L., Dwivedi, S. B., Telikicherla, D., Selvan, L. D. N., Goel, R., Mathivanan, S. et al. (2009). A compendium of potential biomarkers of pancreatic cancer. PLoS Medicine. 6, e1000046.

 

Mathivanan, S. and Pandey, A. (2008). Human Proteinpedia as a resource for clinical proteomics. Mol Cell Proteomics. 10, 2038-47.

 

Mathivanan, S., Ahmed, M. et al. (2008). Human Proteinpedia enables sharing of human protein data. Nature Biotechnology. 26, 164-7.

 

Molina, H., Horn, D. M., Tang, N., Mathivanan, S. and Pandey, A. (2007). Global Proteomic Profiling of Phosphopeptides using Electron Transfer Dissociation Tandem Mass Spectrometry. Proceedings of the National Academy of Sciences, USA. 104, 2199-2204.

 

Amanchy, R., Periaswamy, B., Mathivanan, S., Reddy, R., Tattikota, S. G. and Pandey, A. (2007). A compendium of curated phosphorylation-based substrate and binding motifs. Nature Biotechnology. 25, 285-286. 

 

Mathivanan, S., Periaswamy, B., Gandhi, T. K. B., Kandasamy, K., Suresh, S., Mohmood, R., Ramachandra, Y. L. and Pandey, A. (2006). An Evaluation of Human Protein-Protein Interaction Data in the Public Domain. BMC Bioinformatics. 7, S19.

 

Gandhi, T. K. B., Zhong, J., Mathivanan, S. et al. (2006). Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets. Nature Genetics. 3, 285-293.