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STA2AS/BS/MS Applied Statistics/Biostatistics/Medical Statistics

STA1LS Statistics for Life Science

STA1SS Statistical Science (5 lectures)

HCS4RSP Research Methods for Speech Pathology

STA4AMD Medical Data Analysis

STA1PSY Statistics for Psychology (3 lectures)

1. KP Leong, EYY Chong, KO Kong, SP Chan, BYH Thong, TY Lian, HH Chng, ET Koh, CL Teh, TC Lau, WG Law, YK Cheng, H Badsha, CL Ching, WH Yong, HS Howe, TTSH Lupus Study Group. Discordant assessment of lupus activity between patients and their physicians; the Singapore experience. Lupus 2010; 19(1): 100-106.  
2. R Lee, SP Chan, J Wong, D Lau, KT Ho, K Ng. Impact of diabetes mellitus on survival in South East Asian patients with congestive heart failure due to left ventricular systolic dysfunction. International Journal of Cardiology 2010; 142(1):97-100. 
3. GW Tan, SP Chan, CK Ho. Is transurethral catheterisation the ideal method of bladder drainage? A survey of patient satisfaction with indwelling transurethral urinary catheters. Asian Journal of Surgery 2010; 33(1): 31-36.  
4. PK Chong, H Lee, J Zhou, SC Liu, MC Loh, TT Wang, SP Chan, OT Smoot, H Ashktorab, JB So, KH Lim, KG Yeoh, YP Lim. ITIH3 is a potential biomarker for early detection of gastric cancer. Journal of Proteome Research 2010; 9(7): 3671-3679.  
5. PK Chong, H Lee, MC Loh, LY Choong, Q Lin, JB So, KH Lim, RA Soo, WP Yong, SP Chan, OT Smoot, H Ashktorab, KG Yeoh, YP Lim. Unregulation of plasma C9 protein in gastric cancer patients. Proteomics 2010; 10(18): 3210-3221.  
6. MK Leow, SP Chan. Cardiovascular events and calcium supplements—A call for reappraisal. British Medical Journal (13 August 2010).  
7. MN Nga, NNM Swe, KT Chen, L Shen, MB Lilly, M Salto-Tellez, SP Chan, K Das. PPIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications. International Journal of Experimental Pathology, 2010: 91: 34-43.  
8. WC Wong, SP Chan, YY Ding, S Sahadevan. Resource allocation in hospitalized, older patients. Annals of Academy of Medicine Singapore 2010; 39(11): 830-836.  
9. MS Chong, WS Lim, SP Chan, L Feng, M Niti, P Yap, D Yeo, TP Ng. Diagnostic performance of Chinese Frontal Assessment Battery (FAB) in early cognitive impairment in an Asian population. Dementia & Geriatric Cognitive Disorders 2010; 30(6): 525-532.  
10. R Dalan, M Jong, SP Chan, R Hawkins, R Choo, B Lim, ML Tan, MKS Leow. High sensitive C—reactive protein (hs-CRP) concentrations among Patients with and without Diabetes in a Multi-ethnic Population of Singapore: CREDENCE Study. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2010; 3: 187-195.  
11. KC Poh, HY Lee, MCS Loh, WT Lim, SP Chan, RA Soo, YP Lim. Hemoglobin subunit beta (HBB) is a potential biomarker for predicting response to Gefitinib in NSCLC patients. Journal of Integrated OMICS 2011 2011; 1(2): 297-304.  
12. CA Unsworth, A Barker, C Taitz, SP Chan, JF Pallant, KJ Russell, M Odell. Development of a standardized Occupation therapy: Driver off-Road Assessment (OT-DORA) battery to assess older and/or functionally impaired drivers. Australian Occupational Therapy Journal 2012; 59(1): 23-36.  
13. BF Assiddiq, KY Tan, W Toy, SP Chan, PK Chong, YP Lim. EGFR S1166 Phosphorylation induced by a combination of EGF and Gefitinib has a potentially negative impact on lung cancer cell growth. Journal of Proteome Research 2012; 11(8): 4110-4119.  
14. A Chow, OA Arah, SP Chan, BF Poh, P Krishnan, WK Ng, S Choudhury, J Chan, B Ang. Alcohol handrubbing and chlorhexidine handwashing protocols for routine hospital practice: A randomized clinical trial of protocol efficacy and time effectiveness.American Journal of Infection Control 2012.  
15. D Low, S Low, KK Lee, SP Chan, BT Ang. Post-traumatic hydrocephalus: a review of indications and results after ventricular shunt placement in a Singapore neurological unit. Journal of Clinical Neuroscience 2012 (to appear).  
16. G Farrell, T Shafiel, SP Chan. Patient and visitor assault (PVA) on nurses and midwives: Protective and risk factors.  International Journal of Mental Health Nursing 2012 (to appear).  
17. M Taylor, D Horey, SP Chan, C Livingstone, H Swerissen. Decline with capital D Part II: providing less or none at all. Australian Health Review 2012 (to appear).
18. J Schuijers, S McDonald, B Julien, L Lexis, C Thomas, SP Chan, T Samiric. Effectiveness of separating theory and practicum as a condutit to learning physiology. Advances in Physiological Education 2013 (to appear).

1. J Thumboo, KY Fong, SP Chan, KH Leong, PH Feng, ST Thio, ML Boey. The Rheumatology Attitudes Index and its helplessness subscales are valid and reliable measures of learned helplessness in Asian patients with systemic lupus erythematosus. Journal of Rheumatology 1999; 26(7): 1512-1517.  
2. J Thumboo, KY Fong, SP Chan, KH Leong, PH Feng, ST Thio, ML Boey. Validation of the Medical Outcomes Study Family and Marital Function Measures in SLE patients in Singapore. Lupus 1999; 8(7): 514-520.  
3. ET Koh, AUJ Yap, CKH Koh, TSG Chee, SP Chan, IC Boudville. Temporomandibular disorders in rheumatoid arthritis. Journal of Rheumatology 1999; 26(9): 1918-1922.  
4. KP Leong, SP Chan, CY Tang, SCL Yeak, ASM Saurajen, PKH Mok, JK Siow, NWC Chee, R Seshadri, SB Yeo, LC Khoo, JCY Lee, HH Chng. Quality of Life of patients with perennial allergic rhinitis: preliminary validation of the Rhinoconjunctiviitis Quality of Life Questionnaire in Singapore. Asian Pacific Journal of Allergy & Immunology 1999; 17(3): 163-167. 
5. S Sahadevan, JPP Lim, NJL Tan, SP Chan. Diagnostic performance of two mental status tests in the older Chinese: influence of education and age on cut-off values. International Journal of Geriatric Psychiatry 2000; 15(3): 234-241.  
6. HC Chua, N Venketasubramania, H Tjia, SP Chan. Elimination of phenytoin in toxic overdose. Clinical Neurology & Neurosurgery 2000; 102 (1): 6-8. 
7. J Thumboo, KY Fong, SP Chan, KH Leong, PH Feng, ST Thio, ML Boey. A prospective study of factors affecting quality of life in SLE. Journal of Rheumatology2000; 27(6): 1414-1420.  
8. CBE Chee, IC Boudville, SP Chan, YK Zee, YT Wang. Patient and disease characteristics, and outcome of treatment defaulters from the Singapore TB Control Unit—a one-year retrospective survey.   International Journal of Tuberculosis and Lung Disease 2000; 4(6): 496-503.  
9. J Thumboo, HY Lee, KY Fong, SP Chan, CAT Chapman, KH Leong, PH Feng, ML Boey.    Accuracy of medical record scoring of the SLICC/ACR Damage Index for systemic lupus erythematosus.   Lupus 2000; 9(5): 358-362.  
10. T Aung, PJ Foster, SKL Seah, SP Chan, WK Lim, HM Wu, ATH Lim, L Lee, SJ Chew. Trabeculectomy for acute primary angle disclosure. Ophthalmology 2000; 107(7): 1298-1302.  
11. YY Sitoh, A Lee, PK Lieu, SY Phua, SP Chan. Bedside assessment of swallowing—a useful screening tool for dysphagia in an acute geriatric ward. Singapore Medical Journal 2000; 41 (8): 376-381.  
12. CHB Ho, J Laudette-Aboulhab, SY Se-Thoe, SP Chan, AE Ling, YS Leo. Correlation of baseline quantitative plasma human immunodeficiency (HIV) Type 1 RNA viral load with clinical status and CD4+ T-cell counts in treatment-naïve HIV-positive patients in Singapore. Annals of Academy of Medicine Singapore 2000; 29 (6): 708-713.  
13. T Aung, LPK Ang, SP Chan, PTK Chew. Acute primary angle-closure: long-term intracoular pressure outcome in Asian eyes. American Journal of Ophthalmology 2001; 131(1): 290-295.  
14. WS Yap, CC Chan, SP Chan, YT Wang. Ethnic difference in anthropometry among adult Singaporean Chinese, Malays and Indians, and their effects on lung volumes. Respiratory Medicine 2001; 95(4): 297-304.  
15. T Aung, PJ Foster, SKL Seah, SP Chan, WK Lim, HM Wu, ATH Lim, L Lee, SJ Chew: Automated static perimetry: the influence of myopia and its method of correction. Ophthalmology 2001; 108(2): 290-295.  
16. J Thumboo, KY Fong, D Machin, SP Chan, KH Leong, PH Feng. A community-based study of scaling assumptions and construct validity of the English (UK) and Chinese (HK) SF-36 in Singapore. Quality of Life Research 2001; 10(2): 175-188.  
17. N Paton, CAT Chapman, SP Chan, KM Tan, YS Leo, J Aboulhab, CH Soh. Validation of the medical outcomes study HIV health survey as a measure of quality of life in HIV-infected patients in Singapore. International Journal of Sexually Transmitted Diseases and AIDS 2002; 13: 456-461.  
18. J Thumboo, KY Fong, D Machin, CH Soh, SP Chan, KH Leong, PH Feng, ST Thio, ML Boey.    Does being bilingual in English and Chinese influence responses to quality-of-life scale? Medical Care 2002; 40(2): 105-112. 
19. J Thumboo, PH Feng, SP Chan, ML Boey, ST Thio, KY Fong. A Chinese version of the Rheumatology Attitudes Index is a valid and reliable measure of learned helplessness in patients with SLE. Lupus 2002; 11(2): 88-94.  
20. S Sahadevan, JPP Lim, NJL Tan, SP Chan. Psychometric identification of early alzheimer disease in an elderly Chinese population with differing educational levels. Alzheimer Disease and Associated Disorders 2002; 16(2): 65-72.  
21. J Thumboo, KY Fong, SP Chan, D Machin, PH Feng, ST Thio, ML Boey. The equivalence of English and Chinese SF-36 versions in bilingual Singapore Chinese. Quality of Life Research 2002; 11(5): 495-503.  
22. H Badsha, KO Kong, TY Lian, SP Chan, CJ Edwards, HH Chng. Low-dose pulse methylprednisolone for systemic lupus erythematosus flares is efficacious and has a decreased risk of infectious complications. Lupus 2002; 11(8): 508-513.  
23. KC Ong, CM Loo, YY Ong, SP Chan, A Earnest, SM Saw. Predictive values for cardiopulmonary exercise testing in sedentary Chinese adults. Respirology 2002; 7(3): 225-231.  
24. J Thumboo, SP Chan, D Machin, CH Soh, PH Feng, ML Boey, KH Leong, ST Thio, KY Fong. Measuring health-related quality of life in Singapore: normal values for the English and Chinese SF-36 Health Survey. Annals of Academy of Medicine Singapore 2002; 31 (3): 366-374.  
25. FS Lim, MPHS Toh, SC Emmanuel, SP Chan, G Lim. A preliminary evaluation of a disease management programme for patients with diabetes mellitus and hypertension in a primary healthcare setting. Annals of Academy of Medicine Singapore 2002; 31 (4): 431-439.  
26. KC Ng, QW Yong, SP Chan, A Cheng. Homocysteine, folate and viatmin B12 as risk factors for acute myocardial infarction in a Southeast Asian population. Annals of Academy of Medicine 2002; 31 (5): 636-640. 
27. J Lim, RC Hawkins, K Ng, SP Chan, A Cheng, KS Ng. A preliminary study of the utility of combined cardiac markers in the evaluation of patients presenting early with suspected acute coronary syndrome. Annals of Academy of Medicine Singapore 2002; 31 (6):772-776.  
28. KC Chan, E Seow, G Lau, SP Chan, KY Tham. Female trauma patients in the emergency department: should their injury prevention programme be different? Hong Kong Journal of Emergency Medicine 2003; 10(1): 13-18.  
29. FM Chan, R Mathur, JJK Ku, CC Chen, SP Chan, VSH Yong, KG Au Eong. Short-term outcomes of eyes with posterior capsule rupture during cataract surgery. Journal of Cataract and Refractive Surgery 2003; 29(3): 535-541.  
30. SJ Chia, CT Heng, SP Chan, KT Foo. Correlation of intravesical prostatic protrusion with bladder outlet obstruction. British Journal of Urology International 2003; 91(4): 371-374.  
31. J Thumboo, KY Fong, D Machin, SP Chan, CH Soh, KH Leong, PH Feng, ST Thio, ML Boey. Quality of life in an urban Asian population: the impact of ethnicity and socio-economic status. Social Science & Medicine 2003; 56(8): 1761-1772.  
32. TY Lian, CJ Edwards, SP Chan, HH Chng. Reversible acute gastrointestinal syndrome associated with active systemic lupus erythematosus in patients admitted to hospital. Lupus 2003; 12(8): 612-616.  
33. KP Leong, YP Lee, SP Chan. Why lupus patients use alternative medicine? Lupus 2003; 12(8): 659-664.  
34. R Raja, AV Lim, YP Lim, G Lim, SP Chan, CK Vu. Malnutrition screening in hospitalised patients and its implications on reimbursement. Internal Medicine Journal 2004; 34: 176-181.  
35. K Vijaya, SP Chan, YY Low, LL Foo, M Lee, M Deurenberg-Yap. Public knowledge, attitude, behaviour and response to the SARS outbreak in Singapore. International Journal of Health Promotion and Education 2004; 42(3): 78-82.  
36. WS Lim, HN Low, SP Chan, HN Chen, YY Ding, TL Tan. Impact of a pharmacist consult clinic on a hospital-based geriatric outpatient clinic in Singapore. Annals of Academy of Medicine Singapore 2004; 33: 220-227.  
37. KP Leong, KO Kong, BY Thong, ET Koh, TY Lian, CL Teh, YK Cheng, HH Chng, H Badsha,WG Law, TC Lau, LC Chew, HJ Ho, LY Pong, LS Hoi, S Nagarajan, SP Chan, HS Howe. Psychometric properties of a new systemic lupus erythematosus-specific quality-of-life instrument (SLEQOL).Annals of Academy of Medicine Singapore 2004; 33(5 Supplement): S35-37.  
38. SP Chan, KL Poh. A meta-analysis of the tolerability of selective serotonin reuptake inhibitors and tricyclic antidepressants for treating patients with depression. Singapore General Hospital Proceedings 2005; 14 (1): 17-27.  
39. K Vijaya, YY Low, SP Chan, LL Foo, M Lee, M Deurenberg-Yap. Behaviour of Singaporeans during the SARS outbreak: the impact of anxiety and public satisfaction with media information. International Journal of Health Promotion and Education 2005.  
40. E Tay, SKL Seah, SP Chan, ATH Lim, SJ Chew, PJ Foster, T Aung. Optic disc ovality as an index of tilt, and its relationship with myopia and perimetry. American Journal of Ophthalmology 2005; 139: 247-252.  
41. KP Leong, KO Kong, BY Thong, ET Koh, TY Lian, CL Teh, YK Cheng, HH Chng, H Badsha, WG Law, TC Lau, LC Chew, HJ Ho, LY Pong, LS Hoi, S Nagarajan, SP Chan, HS Howe. Development and preliminary validation of a systemic lupus erythematosus-specific quality-of-life instrument (SLEQOL). Rheumatology 2005; 44(10): 1267-1276.  
42. KP Leong, SCL Yeak, ASM Saurajen, PKH Mok, A Earnest, JK Siow, NWC Chee, SB Yeo, MLC Khoo, JCY Lee, R Seshadri, SP Chan, CY Tang, HH Chng. Why generic and disease-specific quality-of-life instruments should be used together for the evaluation of patients with persistent allergic rhinitis. 2005. Clinical Experimental Allergy 2005; 35(3): 288-298.  
43. M Deurenberg-Yap, LL Foo, YY Low, SP Chan, M Lee, K Vijaya. The Singaporean response to the SARS outbreak: knowledge sufficiency versus public trust. Health Promotion International 2005; 20(4): 320-326.  
44. Chong, JJ Chin, SM Saw, SP Chan, N Venketasubramanian, LCS Tan, CY Hong, S Sahadevan. Screening for dementia in the older Chinese with a single question test on progressive forgetfulness. International Journal of Geriatric Psychiatry 2006; 21(5): 442-448.  
45. SP Chan, CC Teo, SA Ng, N Goh, C Goh, M Deurenberg-Yap. Validation of various osteoporosis risk indices in elderly Chinese females in Singapore. Osteoporosis International 2006; 17(8): 1182-1188.  
46. CL Ang, KG Au Eong, SS Lee, SP Chan, CS Tan. Patients' expectation and experience of visual sensations during phacoemulsification under topical anaesthesia. Eye 2006; 9(21): 1162-1167.  
47. KVijaya, SP Chan, HPC Ho, Y Lim, R Lim. HPB Online: an electronic health education tool in Singapore. Singapore Medical Journal 2006;47 (1): 8-13.  
48. FM Chan, R Mathur, JJ Ku, C Chen, SP Chan, VS Yong, KG Au Eong. Rates of posterior capsule rupture during cataract surgery among different races in Singapore. Annals of Academy of Medicine Singapore 2006; 35(10): 698-700.  
49. ML Wong, SP Chan. Oral health knowledge, attitudes and practices of adult Singaporeans. Singapore Dental Journal 2006; 28(1): 54-60.  
50. SP Chan. Beta regression analysis of Singapore general election results. 2nd IMT-GT Regional Conference on Mathematics, Statistics and their Applications.  
51. VJM Lee, MI Chen, SP Chan, CS Wong, J Cutter, KT Goh, PA Tambyah. Influenza pandemics in Singapore, a tropical, globally connected city. Emerging Infectious Disease 2007; 13(7): 1052-1057.  
52. AM Tow, KL Toh, SP Chan, D Consigliere. Botulinum toxin type A for refractory detrusor overactivity in spinal cord injured patients in Singapore. Annals of Academy of Medicine Singapore 2007; 36(1): 11-17.  
53. C Soh, P Rajoo, SP Chan, SB Samat. An outcome study of cardiac rehabilitation in an outpatient setting in Singapore. Physiotherapy Singapore 2007.  
54. MF Back,EL Ang, WH Ng, SJ See, CC Lim,SP Chan, TT Yeo. Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy. Annals of Academy of Medicine Singapore 2007; 36(5): 338-345. 
55. Sule, AA, DYH Tai, SP Chan, P Handa, JC Tay. Outcome of blood pressure and renal function in patients with renal artery stenosis after stenting. International Journal of Angiology 2007, 16(4): 131-134.  
56. GGQ Xu, SS Sathappan, JJ Sen, SP Chan, CH Lai. A review of clinical pathway data of 1663 total knee arthroplasties in a tertiary institution in Singapore. Annals of Academy of Medicine Singapore 2008; 37(11): 924-928.  
57. CS Wong, HC Tan, CJ Goh, SP Chan, VJM Lee, YS Leo. Dengue infections in HIV patients. Southeast Asian Journal of Tropical Medicine and Public Health 2008; 39(2): 260-265.  
58. K Chua, KH Kong, SP Chan. Prevalence and risk factors of asymptomatic lower extremity deep venous thrombosis in Asian neurorehabilitation admissions in Singapore. Archives of Physical Medicine and Rehabilitation 2008; 89(12): 2316-2323.   
59. BT Ang, SP Chan, KK Lee, I Ng. Prediction of early mortality in primary intracerebral hemorrhage in an Asian population. Acta Neurochirurgica Supplements 2008; 102: 299-303.  
60. AWC Kow, A. Tan, SP Chan, SF Lee, CY Chan, KH Liau, CK Ho. An audit of ambulatory laparoscopic cholecystectomy in a Singapore institution: are we ready for day-case laparoscopic cholecystectomy?Hepato Pancreato Biliary 2008; 10(6):433-8.  
61. AWC Kow, SP Chan, A. Earnest, CY Chan, K. Lim, SY Chong, KH Lim, CK Ho, SP Chew, KH Liau. Striving for a better operative outcome: 101 Pancreaticoduodenectomies. Hepato Pancreato Biliary 2008; 10(6): 464–471.  
62. MK Leow, KC Loh, M Zhu, SP Chan, FX Sundram. Iodine-131 therapy for hyperthyroidism Prescribed by endocrinologist—our preliminary experience. Experimental and Clinical Endocrinology & Diabetes 2009; 117(10):616-21.  
63. R Lee, SP Chan, YH Chan, J Wong, D Lau, K Ng. Impact of race on morbidity and mortality in patients with congestive heart failure: a study of the multiracial population in Singapore. International Journal of Cardiology 2009; 29; 134(3):422-5.  
64. YE Liu, S Hu, SP Chan, SS Sathappan. The epidemiology and surgical outcomes of patients undergoing primary total hip replacement: an Asian perspective. Singapore Medical Journal 2009; 50(1): 15-19.  
65. IY Leong, SP Chan, BY Tan, YY Sitoh, YH Ang, R Merchant, K Kanagasabai, PS Lee, WS Pang. Factors affecting unplanned readmissions from community hospitals to acute hospitals: a prospective observational study. Annals of Academy of Medicine Singapore 2009; 38(2): 113-120.  
66. GGQ Xu, SP Chan, ME Puhaindran, WYC Chew. Prospective randomised study of intra-articular fractures of the distal radius: comparison between external fixation and plate fixation. Annals of Academy of Medicine Singapore 2009; 38(7): 600-606.  
67. L Ye, KO Lee, LP Su LP, WC Toh, HK Haider, PK Law, W Zhang, SP Chan, EK Sim. Skeletal myoblast transplantation for attenuation of hyperglycaemia, hyperinsulinaemia and glucose intolerance in a mouse model of type 2 diabetes mellitus.Diabetologia 2009, 52(9):1925-1934.  
68. VJM Lee, J Yap, J Ong, SP Chan, KT Goh, MI Chen. Influenza excess mortality across fifty years in tropical Singapore—1950-2000. PLoS ONE 2009; 4(12): e8096.  

• Business Analytics (applied econometrics, business optimism and empirical legal research)
• Medical Analytics (health systems evaluation, infection control, proteome and probability encoding for decision analysis)
• Road Safety Analytics (with Chair Professor Richard Tay, La Trobe University)
• Structural Equation Modelling (with Agency for Science, Technology & Research, Singapore; applications in clinical trials and model selection)