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Department of Podiatry - Vascular Assessment Obesity
The effects of obesity are related not only to the amount of fat but to the distribution. Central or visceral obesity, where fat accumulates around the trunk and in the abdominal cavity, is considered to be of higher risk than diffusely distributed subcutaneous fat (Cotran, 1999). Obesity increases the risk of several conditions including diabetes, hypertension, hyperlipidaemia, coronary artery disease (Cotran, 1999). The pathomechanics of these relationships is complex, and they are probably interrelated. It is known that obesity is associated with insulin resistance, an important factor in type 2 diabetes (Payne, 2000; Cotran, 1999). It is proposed that hyperinsulinaemia is also involved in sodium retention and hence hypertension.
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