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| Lecturer:
George
Murley |
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| The
skin: |
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-Largest
organ of the body
-Avg.
surface area of 1.8m2
-Makes
up about 16% of body weight
-Referred
to as the ‘integument' or the ‘integumentary
system' |
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Skin
differs in thickness - is thicker in areas of chronic friction |
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Functions
of the Skin
Protection
Sensation
Thermoregulation
Immune system
Metabolism
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Considered
to be three layers:
Epidermis,
dermis and
subcutaneous or subcutis (not always regarded as part of the skin)
Epidermis is outermost layer and is composed of cellular elements
called keratinocytes
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EPIDERMIS:
Stratum
germinativum (basale) - sits on a basement membrane
Stratum
spinosum (prickle layer)
Stratum
granulosum (granular layer)
Stratum
corneum (horney layer)
Stratum
lucidum - palms/soles?
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OTHER
CELLS OF EPIDERMIS:
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NON-KERATINOCYTES:
Melanocytes
Langerhan's
cells
Merkel
cells
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DERMIS:
Dermis divided into 2 regions:
papillary dermis
reticular dermis
Based largely
on differences in size and density of collagen fiber bundles
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CELLS
OF DERMIS:
Fibroblasts:
Macrophages:
Mast cells:
Lymphocytes:
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| Resources: |
| Anatomy
and Histology of Normal Skin from Loyola University |
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