School of Pharmacy and Applied Science
La Trobe University, Bendigo
PO Box 199
Bendigo, Victoria 3552
AUSTRALIA
Tel: +61 3 5444 7351
Fax: +61 3 5444 7476
Email: pharmacy
@latrobe.edu.au
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Staff Profile
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Jasim
Al-Rawi
BSc. Baghdad, Ph.D.
Surrey, MRACI C CHEM |
Senior Lecturer
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Room
Location: Applied Science 1, Room 2.14B
Ph: 5444 7364
Fx: 5444 7476
Email: j.al-rawi@latrobe.edu.au
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Teaching Responsibilities |
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Organic
Chemistry |
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Pharmaceutical
Chemistry |
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Medicinal
chemistry |
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Research
Interests |
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Heterocyclic
Synthesis and Spectroscopy (using 1 H
and 13C NMR, Mass, FTIR, UV, HPLC, and GC) and testing for the biological
effect of selected products. |
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The
direct use of 2-(hydroxy, thio, or amino) aromatic/heteroaromatic
/ 3-oxo carboxylic acids in the synthesis of 1,3-benzoxazine, 1,3-benzothiazine,
quinazoline and 1,3- oxazine derivatives respectivly. These products
can be used in the development of potent antiplatelet drugs. |
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The
reactions of 1,3-oxazines with primary amines to give N-salicyloyl
N-amino thiourea which show antimicrobial activity. |
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The
reactions aryl carbamate with R (CO) CH (X)(CO) Cl then attempting
cyclization of the products which could lead 5,6-dihydro-2H-1,3-benzoxazocine-2,4(3H)-dione
as non-addictive analgesics , Nefopam analogue. |
Professional Memberships |
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Member of Royal Australian Chemical Institute (MRACI C CHEM) |
PhD supervision |
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Kaylene
Pritchard (PhD), Jason McKerrow (PhD) |
Recent Publications |
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Sheat,
Mohammed A. Al-Rawi, Jasim M. A.; Synthesis of 2-substituted-3-oxo-3-
[(aryloxycarbonyl) amino] propanoic acid, ethyl 3-{[(1E)-ethoxy (aryloxy)
methylene] amino}-2-substituted-3-oxopropanoate, (1Z, 2Z) [chloro
(aryloxy) methylene] hydrazines and Structurally Related Compounds
from the Reaction of Alkyl or Aryl malonyl Chlorides with Aryl Cyanates.
Accepted in Asian J. Chem. 2004. |
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Sheat,
Mohammed A.; Al-Rawi , Jasim M. A.; Heterocyclic Synthesis from the
Reaction of Aryl cyanate with Malonyl chloride, and Bromomalonyl chloride
Accepted in Asian J. Chem. 2004. |
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Al-Rawi,
Jasim M. A.; Hanna, Salim Y.; Al-Rhman, Amer A.Solvent effects on
the 1H NMR spectra of some a- (2-hydroxy-1-phenyl)-N- (4-substituted
phenyl) nitrones. Spectrochim. Acta, Part A (1995), 51A(14), 2585. |
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Danil,
Angela F.; Blackett, Peter M.; Cabaleiro, Mercedes C.; Al Rawi, Jasim
M. A. Cyclodextrin-monosaccharide interactions in water. J. Chem.
Soc., Faraday Trans. (1994), 90(6), 845-7. |
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A.
F. Danil de Namor, M. T. G. Parrido, D. A. P. Tanaka, F. J. SuerosVelarde,
J. D. C. Garcia, M.C. Cabaleiro and J. M. A. Al-Rawi. From neutral
to ionic species: Amine-p-tert-butylcalix (n) arene (n = 6, 8) interaction.
Electrochemical, thermodynamic and structural studies in benzonitrile.
J. Chem. Soc., Faraday Trans. (1993) 89(15) 2727-2736. |
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Hanna, Salim Y.; Al-Rawi, Jasim M. A.; Al-Rahman, Amir A. Solvent
effect on a-proton chemical shifts of a, N-diarylnitrones. Spectrochim.
Acta, Part A (1993), 49A(7), 1022 |
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Al-Mousawi,
Ali H.; Al-Rawi, J. M. A.; Al-Ajiely, M. S. Synthesis and antimicrobial
activity of 2-substituted-7-chloro-pyrano [3,4-e][1,3] oxazine-4,
5-dione. Arab Gulf J. Sci. Res. (1991), 9(1), 1-10. 5. |
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Yousif,
Yousif Z.; Al-Rawi, Jasim M. A.
High-resolution proton NMR spectra of bis (2,2'-bipyridine)(4,4'-dialkyl-2,
2’-bipyridine) ruthenium (II) salts. Polyhedron (1992), 11(11),
1411-18. |
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Al-Rawi,
Jasim M. A.; Al-Shahiry, Khalid F. Carbon-13 chemical shift
analysis of 2-thio-3, 4-dihydro-2H-1, 3-benzoxazine-4-ones and their
degradation products with water and amines. J. Environ. Sci. Health,
Part A (1991), A26 (8), 1323-32. |
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Al-Rawi,
Jasim M. A.; Al-Shahiry, Khalid F. Synthesis of 4-oxo-2-thioxo-3,
4-dihydro-2H, 1,3-substituted benzoxazine, their transformation with
water, diazomethane, and amines. Asian J. Chem. (1990), 2(4), 343-50. |
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Rashan,
Luay Jamil; Al-Rawi, Jasim Mohamod
Ali; Nadir, May Tawfiq; Awni, Lina. Synthesis and biological
evaluation of N-salicyloyl-N'-benzylthiourea and 2,2-dimethyl-4-oxo-6-methoxybenzo-1,
3 dioxin. Farmaco (1991), 46(5), 677-83. |
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Al-Rawi,
Jasim M. A.; Saleem, Layla M. N. Carbon-13 NMR chemical shifts
and lanthanide shift reagent.induced cis-trans isomerization of N-cinnamylidenehexyl-,
tert-butyl-, and substituted arylamines. Spectrosc. Lett. (1991),
24(1), 161-71. |
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Hussein,
Salim H.; Ahmed, Badie A.; Al-Kattan, Widad T.; Al-Rawi,
Jasim M. A. A new method for the synthesis of N, N’-disubstituted
picolinic amides. Asian J. Chem. (1991), 3(1), 52-7. |
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Hussein,
Salim H.; Ahmed, Badie A.; Al-Sharook, Marwan M.; Al-Rawi,
Jasim M. A. Synthesis and structural investigation of N-pyridyl-1,
3-dihydroxyisoindolines. Asian J. Chem. (1991), 3(1), 30-7. 11. |
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Yousif,
Yousif Z.; Kamounah, Fadhil S.; Ali, Mahir K.; Al-Rawi,
Jasim M. A. Proton and carbon-13 NMR study of a new class of
bipyridinium liquid crystals. Spectrosc. Lett. (1990), 23(7), 811-20. |
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Al-Rawi,
Jasim M. A.; Daoud, Ramzi Y. Novel carbon dioxide ejection
from 7-chloro-2-alkyl- (or aryl-) mercapto-4, 5-dioxopyrano- (3,4-e)-1,3-oxazine,
and its 8-bromo analog. Iraqi J. Sci. (1989), 30(3), 337-40. |
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Yousif,
Yousif Z.; Jenkins, Aubrey D.; Walton, David R. M.; Al-Rawi,
Jasim M. A. Novel ioneneomeric polymer liquid crystals. Eur.
Polym. J. (1990), 26(8), 901-5. |
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