Research highlights

Making the next generation of biomedical imaging tools

Dr Shan Kou is an expert on 3D nanoscopy, developing ultra-small devices that will provide us with three dimensional images of cells and organelles in their original state.

The small footprint of these devices will lead to the next generation of biomedical imaging tools, making it possible to obtain super-resolved nanoscopy from a standard microscope. Learn more.

Creating a new type of crystal

Dr Brian Abbey and an international team of more than 20 scientists have discovered how to create a new type of crystal using light more than ten billion times brighter than the sun.

Using the world’s first hard X-ray free electron laser, the researchers exposed the crystals to intense light. The electrons in the crystals spontaneously re-arranged their positions, changing the shape of the molecules completely. Their findings, published in Science Advances, reverse what has been accepted thinking in crystallography for more than 100 years. Read more.

Discovering proteins critical to gene regulation

Turning genes on or off at the right time and right places is critical to human development and health. Abnormal gene regulation often results in cancer and other disorders.

Dr Mihwa Lee, in collaboration with researchers from the University of Western Australia, reported the first structure of SFPQ, a human protein that plays an important role in gene regulation. Uncovering the molecular detail of this protein will allow scientists to further examine its multifunctional role in the cell nucleus. Read more.

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