Members

Theme Leaders

Humbert - Cancer biology, cell polarity and tissue architecture

Our laboratory is interested in how cell asymmetry and tissue organisation can regulate cancer initiation, progression and metastasis.

Parker - Cancer microenvironment and immunology

Our group studies the mechanisms of cancer cell spread (metastasis) to distant tissues and organs.


Members

Cutts - Cellular responses to anticancer drugs

Our group develops new therapeutic strategies for cancer treatment. We examine the mechanism of action of available anticancer drugs and work to restrict the killing properties to cancerous cell types.


Greening - Extracellular vesicles, exosomes, cancer biology and uterine biology

Our group uses an integrated system biology approach to understand extracellular communication in the context of the tumour microenvironment and uterine development.


Hart - Molecular regulation of stem cells and cancer

Our group studies the key genes and molecular pathways that regulate stem cells during normal growth and development. We are working to identify how these genes are re-activated in the adult to cause cancer.


Hawkins - Cell death regulation in cancer and viral infection

Our group examines apoptotic regulation in normal cells, cancerous cells and virally-infected cells. We use this knowledge to explore better and safer therapies for cancer and viral diseases.


Hoogenraad - Development of therapeutic antibodies against cachexia

Our group specialises in cancer cachexia, a complication of cancer that is responsible for around 25% of cancer deaths.


Hulett - Inflammation and tumour progression

Our group studies the molecular basis of tumour progression and inflammatory disease to develop novel anti-cancer and anti-inflammatory drugs.


Humbert - Cancer biology, cell polarity and tissue architecture

Our laboratory is interested in how cell asymmetry and tissue organisation can regulate cancer initiation, progression and metastasis.


Lee - Apoptosis, autophagy, cancer, cell biology, biochemistry, structural biology, drug discovery

Our group examines the molecular mechanisms underlying cell fate decisions dictated by the processes of apoptosis and autophagy.


Mathivanan - Exosomes, secretome and systems biology

Our group explores the role of extracellular matrix components (soluble secreted proteins and extracellular vesicles) in cancer and intercellular communication.


Pakay - Signal transduction, cancer biology and bioenergetics

I am interested in understanding how signal transduction events affect cellular and mitochondrial bioenergetics.


Richardson - Cell polarity, cell signalling and cancer

Our group uses the vinegar fly, Drosophila, to model cancer with the vision of understanding how regulators of cell shape (polarity) and the cell skeleton (actin cytoskeleton) impact on cell signalling and cancer development.


Simpson - Cancer secretome, extracellular communication, exosome and extracellular vesicle biology

Our group utilizes an integrated proteomic/genomic strategy to understand the role of the extracellular environment in cancer progression.


Tran - Interactions of x-rays with matter, optical coherence, x-ray imaging

Our group researches various forms of propagation-based x-ray imaging, and are developing quantitative full field imaging techniques using polychromatic x-ray sources.

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