Bone and cartilage

Study in this area ranges from normal bone metabolism to fracture repair.

The Tissue and Cell Biology Group within the Musculoskeletal Research Centre consists of a four laboratories. These laboratories are investigating physiological, pharmacological and pathological aspects of various musculoskeletal (and associated) tissues. Dr Brian Grills leads the Bone and Fracture Laboratory and its main areas of interest include investigating novel biological aspects associated with fracture healing, bone cell biology and bone diseases such as osteoporosis. The Tendon Laboratory led by Dr Tom Samiric is examining molecular aspects of extracellular matrix changes that occur in overuse tendinopathy.

Dr Chris van der Poel is head of the Skeletal Muscle Laboratory. Research in this lab is focussed on understanding mechanisms responsible for changes in skeletal muscle structure and function as a consequence of ageing, osteoarthritis and neuromuscular diseases such as the muscular dystrophies and ALS. Dr Ross O’Shea leads the Neural Injury Laboratory and is investigating novel strategies that protect against neuronal injury, particularly the neuroprotective potential of brain astrocytes.  A number of common pathological mechanisms underlie neuronal death in a range of neurodegenerative diseases, but current treatments are not able to reverse these changes.

Potential PhD topics

The Department will consider any research topic that interests potential PhD students; however, students will benefit from researching in areas that align with the Faculty’s research strengths.  Please find a relevant supervisor to discuss your PhD topic.

Alternatively you may contact one of our academics below to discuss your area of interest.