About CS&CE
Prospective Students
Research
Staff
Dept Comp Sci & Comp Eng
Contact Details
La Trobe University
Victoria 3086
AUSTRALIA
Tel: +61 3 9479 1107
Fax: +61 3 9479 3060
Email: info
@cs.latrobe.edu.au
|
 |
Research - Current Postgraduates - Details
Department of Computer Science & Computer Engineering
| Lee, Nung Kion |
|
Course:
|
PhD |
|
Research Title/Topic:
|
Soft Computing Approaches for Motif Discovery |
|
Supervisor:
|
Assoc. Prof. Justin Wang & Prof. N. J. Hoogenraad |
Description:
Identification of DNA sequence transcription factor binding sites (TFBS) in biological sequences is an important problem.
Current approaches still achieve averagely low recognition rate owing mainly to low signal to noise ratio and variability binding sites.
My research focused on the discovery of TFBS using soft computing approaches specifically neural networks and genetic algorithm (GA).
The motif discovery is approached from the perspective of unsupervised learning in neural networks. Whereas in GA a more efficient multi-model search problem will be targeted. Innovation in both algorithms and architectural design will be proposed in this research. |
|
|
