Dr Peter Barnard
Selected Publications
2004
- P. J. Barnard, M. V. Baker, S. J. Berners-Price, B. W. Skelton, A. H. White, “Dinuclear gold(I) complexes of bridging bidentate carbene ligands: synthesis, structure and spectroscopic characterization” Dalton Trans., 2004, 7, 1038-1047. * This paper was one of Dalton Transactions ten most accessed articles in March 2004 and was the subject of highlight articles in The Royal Society of Chemistry’s Chemical Science magazine, Chem. Sci., 2004, 5, C36, and Chemistry World, 2004, 1, 22.
- P. J. Barnard, M. V. Baker, S. J. Berners-Price, D. A. Day, “Mitochondrial permeability transition induced by dinuclear gold(I)-carbene complexes: potential new antimitochondrial antitumour agents” J. Inorg. Biochem., 2004, 98, 1642-1647.
2005
- M. V. Baker, P. J. Barnard, S. K. Brayshaw, J. L. Hickey, B. W. Skelton, A. H. White, “Synthetic, structural and spectroscopic studies of (pseudo)halo(1,3-di-tert-butylimidazol-2-ylidine)gold complexes” Dalton Trans., 2005, 1, 37-43.
- P. J. Barnard, A. Levina, P. A. Lay, “Cr(V)-peptide complexes: synthesis and spectroscopic characterization” Inorg. Chem., 2005, 44, 1044-1053.
- P. J. Barnard, R. S. Vagg, “A spectroscopic investigation of the self-association and DNA binding properties of a series of ternary ruthenium(II) complexes” J. Inorg. Biochem., 2005, 99, 1009-1017.
- M. V. Baker, P. J. Barnard, S. J. Berners-Price, S. K. Brayshaw, J. L. Hickey, B. W. Skelton and A. H. White, “Synthesis and structural characterization of linear Au(I) N-heterocyclic carbene complexes: New analogues of the Au(I) phosphine drug Auranofin” J. Organomet. Chem., 2005, 690, 5625-5635.
2006
- M. V. Baker, P. J. Barnard, S. J. Berners-Price, S. K. Brayshaw, J. L. Hickey, B. W. Skelton and A. H. White, “Synthesis, structural and anti-mitochondrial studies of cationic linear carbene complexes: potential new anti-tumour agents” Dalton Trans., 2006, 30, 3708-3715.
- P. J. Barnard, M. V. Baker, S. J. Berners-Price, B. W. Skelton, J. H. Steer, L. E. Wedlock and A. H. White, “Dinuclear Gold(I)-carbene complexes: luminescent probes for cellular distribution studies” Angew. Chem. Int. Ed., 2006, 45(36), 5966-5970.
2007
- P. J. Barnard, S. J. Berners-Price, “Targeting the mitochondrial cell death pathway with gold compounds” Coord. Chem. Rev., 2007, 251(13) 1889-1902.
- P. J. Barnard, A. D. Gee, J. R. Dilworth, “New macrocylic diamide ligand systems: potential bifunctional chelators for copper- and gallium-based PET imaging agents” J. Labelled Comp. Rad., 2007, 50(1), S253.
2008
- P. J. Barnard, S. R. Bayly H. E. Betts, P. Bonnitcha, M. Christlieb, J. R. Dilworth and J. P. Holland, “Towards New Copper Based Radiopharmaceuticals” Q. J. Nucl. Med., 2008, 52(2), 174-184.
- J. P. Holland, P. J. Barnard, S. R. Bayly, H. M. Betts, G. C. Churchill, J. R. Dilworth, R. Edge, J. C. Green, and R. Hueting, “Synthesis, radiolabelling and confocal fluorescence microscopy of styrene derivatised zinc and copper bis(thiosemicarbazonato) complexes” Eur. J. Inorg. Chem. 2008, 1985-1993.
- S. I. Pascu, N. Kuganathan, L. H. Tong, R. M. Jacobs, P. J. Barnard, B. T. Chu, C. G. Salzmann, G. Tobias, M. Ward, J. C. Green, M. L.H. Green and J. K. M. Sanders, “Interactions of Tripodal Porphyrin Hosts with Single Walled Carbon Nanotubes and C60: an Experimental and Theoretical (DFT) Account” J. Mater. Chem., 2008, 18(24), 2781-2788.
- P. J. Barnard, S. R. Bayly, J. P. Holland, J. R. Dilworth, P. A. Waghorn, “In vitro assays for assessing the stability of new potential copper-based radiopharmaceuticals” Q. J. Nucl. Med., 2008, 52(2), 174-84.
- J. P. Holland, P. J. Barnard, J. R.Dilworth and D. J. Watkin, “(2-Hydroxyphenylimido-κN)-(methanolato-κO)[2-(2-oxidobenzylideneamino)phenolato-κ2O,N,O']-(triphenylphosphine-κP)rhenium(V)” Acta Crystallogr. E, 2008, E64(6), m773.
- M. M. Jellicoe, S. J. Nichols, B. A. Callus, M. V. Baker, P. J. Barnard, S. J. Berners-Price, J. Whelan, G. C. Yeoh and A. Filipovska, “Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound” Carcinogenesis, 2008, 29(6), 1124-1133.
- J. P. Holland, P. J. Barnard, D. Collison, J. R. Dilworth, R. Edge, J. C. Green, and E. J. L. McInnes, “Spectroelectrochemical and Computational Studies on the Mechanism of Hypoxia Selectivity of Copper Radiopharmaceuticals” Chem.-Eur. J., 2008, 14(19), 5890-5907.
- J. L. Hickey, R. A. Ruhayel, P. J. Barnard, M. V, Baker, S. J. Berners-Price and A. Filipovska “Selective, Mitochondria-Targeted Chemotherapeutics: The Rational Design of Gold(I) N-Heterocyclic Carbene Complexes that are Selectively Toxic to Cancer Cells and Target Protein Selenols in Preference to Thiols” J. Am. Chem. Soc., 2008, 130(38), 12570-12571.
- J. H. Holland, P. J. Barnard, D. Collison, J. R. Dilworth, R. Edge, J. C. Green, J. M. Heslop, E. J. L. McInnes, C. G. Salzmann, A. L. Thompson “Synthesis, X-ray crystallography, spectroelectrochemistry and computational studies on potential copper-based radiopharmaceuticals” Eur. J. Inorg. Chem., 2008, 22, 3549-3560.
- H. M. Betts, P. J. Barnard, S. R. Bayly, J. R. Dilworth, A. D. Gee, J. P. Holland, “Controlled axial coordination: solid-phase synthesis and purification of metallo-radiopharmaceuticals” Angew. Chem. Int. Ed. 2008, 47(44), 8416-8419.
- S. R. Bayly, M. Christlieb, P. J. Barnard, H. M. Betts, J. P. Holland, R. Hueting, R. C. King, F. I. Aigbirhio, J. R. Dilworth, D. J. Honess, P. Wardman, “Bifunctional Chelates for PET Imaging of Hypoxia: In Vitro and in Vivo Evaluation of a Hydrophilic 64Cu-bis(thiosemicarbazonato) Glucose Conjugate” J. Nuc. Med., 2008, 49(11), 1862-1868.
2009
- J. P. Holland, P. J. Barnard, S. R. Bayly, J. R. Dilworth, J. C. Green, “Electronic absorption spectroscopy and time-dependent density functional theory calculations on the nickel(II) complex of 1,4-bis(pyrrol-2-ylmethyleneamino)butane” Inorg. Chim. Acta, 2009, 362(2), 402-406.