Global Utilities

La Trobe University
Science, Technology and Engineering

Dr Belinda Abbott

Selected Publications


  1. Analysis of anti-PDE3 activity by 2-morpholinochromone analogues reveals multiple mechanisms of anti-platelet activity. Abbott, B.M., Thompson, P.E., Bioorganic & Medicinal Chemistry Letters 2006, 16, 969-973.
  2. PI 3-kinase p110b: a new target for antithrombotic therapy. Jackson, S.A., Schoenwaelder, S.M., Goncalves, I., Nesbitt, W.S., Yap, C.L., Wright, C.E., Kenche, V., Anderson, K.E., Dopheide, S.M., Yuan, Y., Sturgeon, S.A., Prabaharan, H., Thompson, P.E. Smith, G.D., Shepherd, P.R., Daniele, N., Kulkarni, S., Abbott, B., Saylik, D., Jones, C., Lu, L., Giuliano, S., Hughan, S.C., Angus, J.A., Robertson, A.D., Salem, H.H., Nature Medicine 2005, 11, 507-514.
  3. A reversed-phase HPLC-based method for the assay of cyclic nucleotide phosphodiesterase activity. Abbott, B., Thompson, P.E., Analytical Biochemistry 2005, 339, 185-187.
  4. PDE2 inhibition by the PI3 kinase inhibitor LY294002 and analogues. Abbott, B., Thompson, P.E., Bioorganic & Medicinal Chemistry Letters 2004, 14, 2847-2851.
  5. Preparation of morpholinyl- and pyridinyl-substituted heterobicyclic ketones as selective inhibitors of phosphoinositide 3-kinase beta for use against thrombosis. Jackson, S.A., Robertson, A.D., Kenche, V., Thompson, P., Prabaharan, H., Anderson, K.E., Abbott, B., Gonclaves, I., Nesbitt, W., Schoenwaelder, S., Saylik, D., PCT International Application 2004, 92 pages, WO 2004/016607 A1, Filed August 18, 2003.
  6. Synthetic Studies of Phosphatidylinositol 3-Kinase Inhibitor LY294002 and RelatedAnalogues. Abbott, B., Thompson, P.E., Australian Journal of Chemistry 2003, 56, 1099-1106.
  7. Photochemical synthesis of benz[h]isoquinolines. Abbott, B.M., Ferrari, F.D., Harnor, S.J. Barnes, J.C., Marquez, R. Tetrahedron 2008, 64(22), 5072-5078