Lee - Apoptosis, autophagy, cancer, cell biology, biochemistry, structural biology, drug discovery
Dr Erinna Lee
ARC Future Fellow, College of Science, Health and Engineering
Our research focuses on understanding the molecular mechanisms underlying cell fate decisions dictated by the processes of apoptosis and autophagy through the use of biochemistry, cell biology and structural biology approaches. In particular, how these pathways when deregulated give rise to cancer and how we can target these fundamental processes with drugs for the treatment of cancer without causing undue harm to an individual.
We are also interested in identifying novel factors that enable crosstalk between these two biological processes which need to be carefully balanced to determine whether a cell lives or dies. As this crosstalk is fundamental to not only normal physiology but can significantly contribute to cancer developlment and treatment, identification of such factors can define new targets for treating diseases in which this crosstalk plays a critical role.