Hong - Fluorescent probes, cell imaging, protein misfolding and neurodegenerative diseases
Bruce Stone Fellow in Chemical Biology, College of Science, Health and Engineering
Our group develops organic luminescent molecules as probes and imaging tools for understanding fundamental biological processes associated with ageing and diseases.
Fluorescence is a powerful technique that could provide spatiotemporal information with exquisite sensitivity. The primary goal of our research is to develop fluorescence-based tools for understanding and manipulating fundamental biological processes. Efforts will be directed towards the design and synthesis of new luminescent molecules in combination with advanced fluorescence spectroscopy and microscopy for monitoring protein conformational transitions associated with neurodegenerative diseases and for tracing biological events in living context.