Science, Technology and Engineering

Postdoctoral Fellow

Department of Biochemistry

Histidine-rich glycoprotein

Dr Ivan Poon BSc(Hons) (Monash), PhD (ANU) Postdoctoral Fellow, Hulett Lab Phone: +61 3 9479 6567 Fax: +61 3 9479 1266 Email: i.poon@latrobe.edu.au Room 216a (Office), 216 (Lab), Physical Sciences 4

Publications

Histidine-rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake. Poon IK, Parish CR, Hulett MD. (2010) J Leukoc Biol. Jun 24.

Histidine-rich glycoprotein binds heparanase and regulates its enzymatic activity and cell surface interactions. Poon IK, Yee DY, Jones AL, Wood RJ, Davis DS, Freeman C, Parish CR, Hulett MD. (2010) Int J Biochem Cell Biol. May 31.

Calmodulin-dependent nuclear import of HMG-box family nuclear factors; importance for the role of SRY in sex reversal. Kaur G, Delluc-Clavieres A, Poon IK, Forwood JK, Glover DJ, Jans DA. (2010) Biochem J. Jun 9.

Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via FcgammaRI on phagocytes. Poon IK, Hulett MD, Parish CR. (2010) Blood. 115(12):2473-82.

Molecular mechanisms of late apoptotic/necrotic cell clearance. Poon IK, Hulett MD, Parish CR. (2010) Cell Death Differ. 17(3):381-97.

Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage. Poon IK, Olsson AK, Hulett MD, Parish CR. (2009) Biochem J. 424(1):27-37.

Interaction with PI3-kinase contributes to the cytotoxic activity of apoptin. Maddika S, Wiechec E, Ande SR, Poon IK, Fischer U, Wesselborg S, Jans DA, Schulze-Osthoff K, Los M. (2008) Oncogene. 27(21):3060-5.

Tumor-specific nuclear targeting: promises for anti-cancer therapy? Alvisi G, Poon IK, Jans DA. (2006) Drug Resist Updat. 9(1-2):40-50.

Histidine-rich glycoprotein specifically binds to necrotic cells via its amino-terminal domain and facilitates necrotic cell phagocytosis. Jones AL, Poon IK, Hulett MD, Parish CR. (2005) J Biol Chem. 280(42):35733-41.

Apoptin nuclear accumulation is modulated by a CRM1-recognized nuclear export signal that is active in normal but not in tumor cells. Poon IK, Oro C, Dias MM, Zhang J, Jans DA. (2005) Cancer Res. 65(16):7059-64.

Regulation of nuclear transport: central role in development and transformation? Poon IK, Jans DA. (2005) Traffic. 6(3):173-86.

A tumor cell-specific nuclear targeting signal within chicken anemia virus VP3/apoptin. Poon IK, Oro C, Dias MM, Zhang JP, Jans DA. (2005) J Virol. 79(2):1339-41.

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