Research Fellow
Department of Biochemistry
Structure and Function of Floral Defensins from the Solanaceae
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Dr Fung T. Lay
BSc(Hons) (La Trobe), PhD (La Trobe)
Research Fellow, Hulett lab
Phone: +61 3 9479 2211 (office), +61 3 9479 2271 (lab)
Fax: +61 3 9479 1266
Email: F.Lay@latrobe.edu.au
Room 220 (office), Room 216 (lab), Physical Sciences 4
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Publications
Lay FT, Mills GD, Hulett MD, Kvansakul M. Crystallization and preliminary X-ray crystallographic analysis of the plant defensin NaD1. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jan 1;68(Pt 1):85-8. Epub 2011 Dec 24.
Dunse KM, Stevens JA, Lay FT, Gaspar YM, Heath RL, Anderson MA. Coexpression of potato type I and II proteinase inhibitors gives cotton plants protection against insect damage in the field. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15011-5. Epub 2010 Aug 9.
Covey PA, Subbaiah CC, Parsons RL, Pearce G, Lay FT, Anderson MA, Ryan CA, Bedinger PA. A pollen-specific RALF from tomato that regulates pollen tube elongation. Plant Physiol. 2010 Jun;153(2):703-15. Epub 2010 Apr 13.
Pelegrini PB, Lay FT, Murad AM, Anderson MA, Franco OL. Novel insights on the mechanism of action of alpha-amylase inhibitors from the plant defensin family. Proteins. 2008 Nov 15;73(3):719-29.
van der Weerden NL, Lay FT, Anderson MA. The plant defensin, NaD1, enters the cytoplasm of Fusarium oxysporum hyphae. J Biol Chem. 2008 May 23;283(21):14445-52. Epub 2008 Mar 13.
Lay FT, Anderson MA. Defensins - components of the innate immune system in plants. Curr Protein Pept Sci. 2005 Feb;6(1):85-101.
Janssen BJ, Schirra HJ, Lay FT, Anderson MA, Craik DJ. Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds. Biochemistry. 2003 Jul 15;42(27):8214-22.
Lay FT, Brugliera F, Anderson MA. Isolation and properties of floral defensins from ornamental tobacco and petunia. Plant Physiol. 2003 Mar;131(3):1283-93.
Lay FT, Schirra HJ, Scanlon MJ, Anderson MA, Craik DJ. The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP. J Mol Biol. 2003 Jan 3;325(1):175-88.
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Honours and Awards
- Student presenter's prize at the inaugural symposium of the Melbourne Protein Group, Australia (2002)
- Student poster prize at the 27th Lorne Conference on Protein Structure and Function, Australia (2002)
- ASBMB student poster prize at the ComBio2000 conference, New Zealand (2000)
- Federation of Asian and Oceanian Biochemists and Molecular Biologists Fellowship (2000)
- Australian Society for Biochemistry and Molecular Biology Fellowship (2000)
- ASBMB student poster prize at the ASBMB/ASPP combined conference, Adelaide (1998)
- Australian Postgraduate Award (1997-2000)
- Unitika Prize for best performance by an Honours student in the Department of Biochemistry, La Trobe University (1996)
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