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Lock LaboratoryDepartment of BiochemistryBiosketch – Dr Peter LockPeter completed a B.Sc with First Class Honours in Biochemistry at La Trobe University in 1984. In 1987, after working as a research assistant and taking time off to travel in Asia and the UK he commenced a Ph.D. at the Melbourne branch of the Ludwig Institute for Cancer Research. His project under Ashley Dunn centred on the regulation of the Src-family kinase, Hck. He joined Nick Nicola's laboratory at the Walter and Eliza Hall Institute of Medical Research as a postdoc in 1991 where he worked on the molecular basis of high affinity binding of GM-CSF to receptor. Peter was awarded fellowships from the Human Frontier Science Program and the Alexander von Humboldt Foundation in 1994, providing the opportunity to join Sara Courtneidge’s group at the European Molecular Biology Laboratory in Germany for 3 years. His main achievement at EMBL was the development of a novel technology to identify substrates of Src tyrosine kinase, which led to his discovery of the Tks5/Fish adaptor protein. Peter returned to the Ludwig Institute for Cancer Research in 1997 and using the strategy he developed at EMBL, identified the DokR and ARAP3 proteins as substrates of Lyn kinase. He established his own laboratory at the University of Melbourne in 2001. His research since then has focussed on the role of phosphorylation in regulating Src substrate function and related to this, the molecular mechanisms of cancer invasion and metastasis.
Current and past research funding:
Past Scholarships and Fellowships:
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Peter joined the Department of Biochemistry at La Trobe in March, 2009.