Science, Technology and Engineering

Klonis Laboratory

Department of Biochemistry

Publications

Knuepfer E, Rug M, Klonis N, Tilley L, Cowman AF. Trafficking of the major virulence factor to the surface of transfected P. falciparum-infected erythrocytes. Blood. 2005 Feb 3; [Epub ahead of print]

Clayton AH, Klonis N, Cody SH, Nice EC. Dual-channel photobleaching FRET microscopy for improved resolution of protein association states in living cells.Eur Biophys J. 2005 Feb;34(1):82-90. Epub 2004 Jun 30.

Jackson KE, Klonis N, Ferguson DJ, Adisa A, Dogovski C, Tilley L. Food vacuole-associated lipid bodies and heterogeneous lipid environments in the malaria parasite, Plasmodium falciparum.Mol Microbiol. 2004 Oct;54(1):109-22.

Taylor DK, Avery TD, Greatrex BW, Tiekink ER, Macreadie IG, Macreadie PI, Humphries AD, Kalkanidis M, Fox EN, Klonis N, Tilley L. Novel endoperoxide antimalarials: synthesis, heme binding, and antimalarial activity. J Med Chem. 2004 Mar 25;47(7):1833-9.

Kalkanidis M, Klonis N, Tschan S, Deady LW, Tilley L. Synergistic interaction of a chloroquine metabolite with chloroquine against drug-resistant malaria parasites. Biochem Pharmacol. 2004 Apr 1;67(7):1347-53.

Parker PD, Tilley L, Klonis N 23 July, 2006 duces reorganization of host membrane proteins during intraerythrocytic growth. Blood. 2004 Mar 15;103(6):2404-6.

Spycher C, Klonis N, Spielmann T, Kump E, Steiger S, Tilley L, Beck HP. MAHRP-1, a novel Plasmodium falciparum histidine-rich protein, binds ferriprotoporphyrin IX and localizes to the Maurer's clefts. J Biol Chem. 2003 Sep 12;278(37):35373-83.

Klonis N, Sawyer WH. The thiourea group modulates the fluorescence emission decay of fluorescein-labeled molecules. Photochem Photobiol. 2003 May;77(5):502-9.

Campanale N, Nickel C, Daubenberger CA, Wehlan DA, Gorman JJ, Klonis N, Becker K, Tilley L. Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparum. J Biol Chem. 2003 Jul 25;278(30):27354-61.

Klonis N, Quazi NH, Deady LW, Hughes AB, Tilley L. Characterization of a series of far-red-absorbing thiobarbituric acid oxonol derivatives as fluorescent probes for biological applications. Anal Biochem. 2003 Jun 1;317(1):47-58.

Adisa A, Rug M, Klonis N, Foley M, Cowman AF, Tilley L. The signal sequence of exported protein-1 directs the green fluorescent protein to the parasitophorous vacuole of transfected malaria parasites. J Biol Chem. 2003 Feb 21;278(8):6532-42.

Klonis N, Rug M, Harper I, Wickham M, Cowman A, Tilley L. Fluorescence photobleaching analysis for the study of cellular dynamics. Eur Biophys J. 2002 Mar;31(1):36-51.

Kalkanidis M, Klonis N, Tilley L, Deady LW. Novel phenothiazine antimalarials: synthesis, antimalarial activity, and inhibition of the formation of beta-haematin. Biochem Pharmacol. 2002 Mar 1;63(5):833-42.

Wickham ME, Rug M, Ralph SA, Klonis N, McFadden GI, Tilley L, Cowman AF. Trafficking and assembly of the cytoadherence complex in Plasmodium falciparum-infected human erythrocytes. EMBO J. 2001 Oct 15;20(20):5636-49.

Brown LJ, Klonis N, Sawyer WH, Fajer PG, Hambly BD. Independent movement of the regulatory and catalytic domains of myosin heads revealed by phosphorescence anisotropy. Biochemistry. 2001 Jul 27;40(28):8283-91.

Klonis N, Sawyer WH. Effect of solvent-water mixtures on the prototropic equilibria of fluorescein and on the spectral properties of the monoanion. Photochem Photobiol. 2000 Aug;72(2):179-85.

Klonis N, Clayton AH, Voss EW Jr, Sawyer WH. Spectral properties of fluorescein in solvent-water mixtures: applications as a probe of hydrogen bonding environments in biological systems. Photochem Photobiol. 1998 May;67(5):500-10.

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