Science, Technology and Engineering

Anders Laboratory

Department of Biochemistry

Publications

Pearce JA, Mills K, Triglia T, Cowman AF, Anders RF. (2005) Characterisation of two novel proteins from the asexual stage of Plasmodium falciparum, H101 and H103. Mol Biochem Parasitol. Feb;139(2):141-51.

Cortes A, Mellombo M, Masciantonio R, Murphy VJ, Reeder JC, Anders RF. (2005) Allele specificity of naturally acquired antibody res23 July, 2006 1. Infect Immun. Jan;73(1):422-30.

Pearce JA, Hodder AN, Anders RF. (2004) The alanine-rich heptad repeats are intact in the processed form of Plasmodium falciparum MSP3. Exp Parasitol. Nov-Dec;108(3-4):186-9.

Fluck C, Smith T, Beck HP, Irion A, Betuela I, Alpers MP, Anders R, Saul A, Genton B, Felger I. (2004) Strain-specific humoral response to a polymorphic malaria vaccine. Infect Immun. Nov;72(11):6300-5.

Healer J, Murphy V, Hodder AN, Masciantonio R, Gemmill AW, Anders RF, Cowman AF, Batchelor A. (2004) Allelic polymorphisms in apical membrane antigen-1 are responsible for evasion of antibody-mediated inhibition in Plasmodium falciparum. Mol Microbiol. Apr;52(1):159-68.

Pearce JA, Triglia T, Hodder AN, Jackson DC, Cowman AF, Anders RF. (2004) Plasmodium falciparum merozoite surface protein 6 is a dimorphic antigen. Infect Immun. Apr;72(4):2321-8.

Nuttall SD, Humberstone KS, Krishnan UV, Carmichael JA, Doughty L, Hattarki M, Coley AM, Casey JL, Anders RF, Foley M, Irving RA, Hudson PJ. (2004) Selection and affinity maturation of IgNAR variable domains targeting Plasmodium falciparum AMA1. Proteins. Apr 1;55(1):187-97.

Rekas A, Adda CG, Aquilina JA, Barnham KJ, Sunde M, Galatis D, Williamson NA, Masters CL, Anders RF, Robinson CV, Cappai R, Carver JA. (2004) Interaction of the Molecular Chaperone aB-Crystallin with a-Synuclein: Effects on Amyloid Fibril Formation and Chaperone Activity. J Mol Biol. 340(5):1167-1183

Stanisic D.I., Martin L.B., Anders R.F. and Good M.F. (2004) Plasmodium falciparum asexual blood-stage vaccine candidates: current status. In Levine M, ed. New Generation Vaccines New York: Marcel Dekker: 875-885.

Casey J.L., Coley A.M., Anders R.F., Murphy V.J., Humberstone K.S., Thomas A.W., Foley M. (2004) Antibodies to Malaria Peptide Mimics Inhibit Plasmodium falciparum Invasion of Erythrocytes. Infect Immun. 72, 1126-1134.

Silvie O., Franetich J.F., Charrin S., Mueller M.S., Siau A., Bodescot M., Rubinstein E., Hannoun L., Charoenvit Y., Kocken C., Thomas A.W., Van Gemert G.J., Sauerwein R.W., Blackman M.J., Anders R.F., Pluschke G., Mazier D. (2004) A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites. J Biol Chem. 279, 9490-9496.

Genton, B., Anders, R.F., Alpers, M.P. and Reeder, J.C. (2003) The malaria vaccine development program in Papua New Guinea. Trends in Parasitology 19, 264-270.

Genton B., Al-Yaman F., Betuela I., Anders R.F., Saul A., Baea K., Mellombo M., Taraika J., Brown G.V., Pye D., Irving D.O., Felger I., Beck H.P., Smith, T.A., Alpers M.P. (2003) Safety and immunogenicity of a three-component blood-stage malaria vaccine (MSP1, MSP2, RESA) against Plasmodium falciparum in Papua New Guinean children. Vaccine 22, 30-41.

Keizer D.W., Miles L.A., Li F., Nair M., Anders R.F., Coley A.M., Foley M., Norton R.S. (2003) Structures of phage-display peptides that bind to the malarial surface protein, apical membrane antigen 1, and block erythrocyte invasion. Biochemistry 42, 9915-23.

Cortes A., Mellombo M., Mueller I., Benet A., Reeder J.C., Anders R.F. (2003) Geographical structure of diversity and differences between symptomatic and asymptomatic infections for Plasmodium falciparum vaccine candidate AMA1. Infect Immun. 71, 1416-26.

Li, F., Dluzewski, A., Coley, A., Casey, J., Tilley, L., Anders, R.F. and Foley, M. (2003) Phage display peptides bind to the malarial protein apical membrane antigen-1 and inhibit the invasion of merozoites into host erythrocytes. Journal of Biological Chemistry, 277, 50303-50310. http://www.jbc.org/cgi/content/full/277/52/50303

Salvatore, D., Hodder, A., Zeng, W., Brown, L., Anders, R., Jackson, D. (2002) Identification of antigenically active tryptic fragments of apical membrane antigen-1 (AMA1) of Plasmodium chabaudi malaria: strategies for assembly of immunologically active peptides. Vaccine 20, 3477.

Nair, M., Hinds, M., Coley, A., Hodder, A., Foley, M., Anders, R., Norton, R. (2002) Structure of Domain III of the Blood-stage Malaria Vaccine Candidate, Plasmodium falciparum Apical Membrane Antigen 1 (AMA1). Journal of Molecular Biology 322, 741.

Genton B., Betuela I., Felger, I., Al-Yaman, F., Anders, R.F., Saul A., Rare L., Baisor, M., Lorry, K., Brown G.V., Pye, D., Irving, D. O., Smith, T. A., Beck, H.P., Alpers, M.P., (2002) A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea. Journal of Infectious Diseases 185, 820-827.

Christopher G. Adda, Robin F. Anders, Leann Tilley and Michael Foley (2002) Random Sequence Libraries Displayed on Phage: Identification of Biologically Important Molecules. Combinatorial Chemistry & High Throughput Screening 5, 1-14.

Nair, M., Hodder, A. N., Hinds, M. G., Anders, R. F. and Norton, R. S. (2001) Assignment of 1H, 13C and 15N resonances of domain III of the ectodomain apical membrane antigen 1 from Plasmodium falciparum. Journal of Biomolecular NMR 19, 85-86.

Hodder, A. N., Crewther, P. E. and Anders, R. F. (2001) Specificity of the protective antibody response to apical membrane antigen 1. Infection and Immunity 69, 3286-3294.

Xu, H., Hodder, A. N., Yan, H., Crewther, P. E., Anders, R. F. and Good, M. F. (2000) CD4+ T cells acting independently of antibody contribute to protective immunology to Plasmodium chabaudi infection after apical membrane antigen 1 immunization. Journal of Immunology 165, 1389-1396.

Triglia, T., Healer, J., Caruana, S. R., Hodder, A. N., Anders, R. F., Crabb, B. S. and Cowman, A. F. (2000) Apical membrane antigen 1 plays a central role in erythrocyte invisation by Plasmodium species. Molecular Microbiology 38, 706-718.

Riley, E. M., Wagner, G. E., Ofori, M. F., Wheeler, J. G., Akanmori, B. D., Tetteh, K., McGuinness, D., Bennett, S., Nkrumah, F. K., Anders, R. F. and Koram, K. A. (2000) Lack of association between maternal antibody and protection of African infants from malaria infection. Infection and Immunity 68, 5856-5863.

Lawrence, G., Cheng, Q. Q., Reed, C., Taylor, D., Stowers, A., Cloonan, N., Rzepczyk, C., Smillie, A., Anderson, K., Pombo, D., Allworth, A., Eisen, D., Anders, R. F. and Saul, A. (2000) Effect of vaccination with 3 recombinant asexual-stage malaria antigens on initial growth rates of Plasmodium falciparum in non-immune volunteers. Vaccine 18, 1925-1931.

Anders, R. F. and Saul, A. (2000) Malaria vaccines. Parasitology Today 16, 444-447.

Adda, C., Tilley, L. M., Anders, R. F. and Foley, M. (1999) Isolation of peptides that mimic epitopes on a malarial antigen from random peptide libraries displayed on phage. Infection and Immunity 67, 4679-4688.

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