Metals in electron-transfer processes
Sulfite is the product of a number of environmental and metabolic processes. It is reactive and must be converted to sulfate. This reaction is mediated by the sulfite oxidizing enzymes. We are examining the sulfite oxidation pathway from the organism Sinorhizobium meliloti. For this bacterium, sulfite oxidation plays a role in energy production and metabolism. Current projects aim to solve the structure of the sulfite oxidase enzyme from Sinorhizobium meliloti (SorT) and those of its likely redox partners (cytochrome c and pseudoazurin) in order to understand the molecular mechanism of sulfite oxidation by this bacterium.
Collaborator: Dr Ulrike Kappler, University of Queensland