Publications

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Coumans FAW, Brisson AR, Buzas EI, Dignat-George F, Drees EEE, El-Andaloussi S, Emanueli C, Gasecka A, Hendrix A, Hill AF, Lacroix R, Lee Y, van Leeuwen TG, Mackman N, Mager I, Nolan JP, van der Pol E, Pegtel DM, Sahoo S, Siljander PRM, Sturk G, de Wever O, Nieuwland R (2017) Methodological guidelines to study extracellular vesicles, Circ Res.,120(10): 1632-48.

Mateescu B, Kowal EJ, van Balkom BW, Bartel S, Bhattacharyya SN, Buzás EI, Buck AH, de Candia P, Chow FW, Das S, Driedonks TA, Fernández-Messina L, Haderk F, Hill AF, Jones JC, Van Keuren-Jensen KR, Lai CP, Lässer C, Liegro ID, Lunavat TR, Lorenowicz MJ, Maas SL, Mäger I, Mittelbrunn M, Momma S, Mukherjee K, Nawaz M, Pegtel DM, Pfaffl MW, Schiffelers RM, Tahara H, Théry C, Tosar JP, Wauben MH, Witwer KW, Nolte-‘t Hoen EN (2017) Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper, J Extracell Vesicles, 7;6(1): 1286095.

EV-TRACK Consortium., Van Deun J, Mestdagh P, Agostinis P, Akay Ö, Anand S, Anckaert J, Martinez ZA, Baetens T, Beghein E, Bertier L, Berx G, Boere J, Boukouris S, Bremer M, Buschmann D, Byrd JB, Casert C, Cheng L, Cmoch A, Daveloose D, De Smedt E, Demirsoy S, Depoorter V, Dhondt B, Driedonks TA, Dudek A, Elsharawy A, Floris I, Foers AD, Gärtner K, Garg AD, Geeurickx E, Gettemans J, Ghazavi F, Giebel B, Kormelink TG, Hancock G, Helsmoortel H, Hill AF, Hyenne V, Kalra H, Kim D, Kowal J, Kraemer S, Leidinger P, Leonelli C, Liang Y, Lippens L, Liu S, Lo Cicero A, Martin S, Mathivanan S, Mathiyalagan P, Matusek T, Milani G, Monguió-Tortajada M, Mus LM, Muth DC, Németh A, Nolte-‘t Hoen EN, O’Driscoll L, Palmulli R, Pfaffl MW, Primdal-Bengtson B, Romano E, Rousseau Q, Sahoo S, Sampaio N, Samuel M, Scicluna B, Soen B, Steels A, Swinnen JV, Takatalo M, Thaminy S, Théry C, Tulkens J, Van Audenhove I, van der Grein S, Van Goethem A, van Herwijnen MJ, Van Niel G, Van Roy N, Van Vliet AR, Vandamme N, Vanhauwaert S, Vergauwen G, Verweij F, Wallaert A, Wauben M, Witwer KW, Zonneveld MI, De Wever O, Vandesompele J, Hendrix A (2017) EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research, Nature Meth.,14(3): 228-32.

Foers AD, Cheng L, Hill AF, Wicks IP, Pang KC (2017) Extracellular vesicles in joint inflammation, Arthritis Rheumatol., doi: 10.1002/art.40076

Quek C, Bellingham SA, Jung CH, Scicluna B, Shambrook MC, Sharples R, Cheng L and Hill AF (2016) Defining the purity of exosomes required for diagnostic profiling of small RNA suitable for biomarker discovery, RNA Biol., 14(2): 245-58.

Quek C and Hill AF (2017) The role of extracellular vesicles in neurodegenerative diseases, Biochem Biophys Res Commun., 2017 Feb 19;483(4):1178-1186.

Cheng L and Hill AF (2017) Small RNA library construction for exosomal RNA from biological samples for the Ion Torrent PGM™ and Ion S5™ System, Methods Mol Biol., 1545: 71-90.

Bellingham SA, Shambrook M and Hill AF (2017) Quantitative analysis of exosomal miRNA via qPCR and digital PCR, Methods Mol Biol., 1545: 55-70.

Howitt J and Hill AF (2016) Exosomes in the pathology of neurodegenerative diseases, J Biol Chem., 291(52): 26589-97.

Gardiner C, Di Vizio D, Sahoo S, Théry C, Witwer KW, Wauben M and Hill AF (2016) Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide survey, J Extracell Vesicles, 5: 32945.

Vogel R, Coumans FA, Maltesen RG, Böing AN, Bonnington KE, Broekman ML, Broom MF, Buzás EI, Christiansen G, Hajji N, Kristensen SR, Kuehn MJ, Lund SM, Maas SL, Nieuwland R, Osteikoetxea X, Schnoor R, Scicluna BJ, Shambrook M, de Vrij J, Mann SI, Hill AF and Pedersen S (2016) A standardized method to determine the concentration of extracellular vesicles using tunable resistive pulse sensing, J Extracell Vesicles, 5: 31242, doi: 10.3402/jev.v5.31242.

Ugalde CL, Finkelstein DI, Lawson VA and Hill AF (2016) Pathogenic mechanisms of prion protein, amyloid-β and α-synuclein misfolding: the prion concept and neurotoxicity of protein oligomers, J Neurochem., 139(2):162-80.

Krämer-Albers E-M and Hill AF (2016) Extracellular vesicles: interneural shuttles of complex messages, Curr Opin Neurobiol., 39: 101-07, doi: 10.1016/j.conb.2016.04.016.

Cheung K-H, Keerthikumar S, Roncaglia P, Subramanian, Roth ME, Samuel M, Anand S, Gangoda L, Gould S, Alexander R, Galas D, Gerstein MB, Hill AF, Kitchen RR, Lotvall J, Patel T, Procaccini DC, Quesenbery P, Rozowsky J, Raffai RI, Shypitsyna A, Su AI, Thery C, Vickers K, Wauben MHM, Mathivanan S, Molisavljevic A and Laurent LC (2016) Extending gene ontology in the context of extracellular RNA and vesicle communication, J Biomed Seman., 7:19, doi: 10.1186/s13326-016-0061-5.

Polanco JC, Scicluna BJ, Hill AF and Gotz J (2016) Extracellular vesicles isolated from brains of rTg4510 mice seed tau aggregation in a threshold-dependent manner, J Biol Chem., doi: 10.1074/jbc.M115.709485 (Epub ahead of print).

François M, Fenech MF, Thomas P, Hor M, Rembach A, Martins RN, Rainey-Smith SR, Masters CL, Ames D, Rowe CC, Lance Macaulay S, Hill AF, Leifert WR and The Australian Imaging Biomarkers and Lifestyle Study Research Group (2016) High content, multi-parameter analyses in buccal cells to identify Alzheimer’s disease, Curr Alzheimer Res., 13(7): 787-99.

Silverman JM, Fernando SM, Grad LI, Hill AF, Turner BJ, Yerbury JJ and Cashman NR (2016) Disease mechanisms in ALS: misfolded SOD1 transferred through exosome-dependent and exosome-independent pathways, Cell Mol Neurobiol., 36(3): 377-81.

Cheng L, Quek CYJ, Hung LW, Sharples RA, Sherratt NA, Barnham KJ and Hill AF (2016) Gene dysregulation is restored in the Parkinson’s disease MPTP neurotoxic mice model upon treatment of the therapeutic drug CuII(atsm), Sci Rep., 6:22398.

Vella LJ, Hill AF and Cheng L (2016) Focus on extracellular vesicles: exosomes and their role in protein trafficking and biomarker potential in Alzheimer’s and Parkinson’s Disease, Int J Mol Sci., 17(2): 173, doi:10.3390/ijms17020173.

Guo BB, Bellingham SA, Hill AF (2016) Stimulating the release of exosomes increases the intercellular transfer of prions, J Biol Chem., pii: jbc.M115.684258 (Epub ahead of print).

Low H, Cheng L, Di Yacovo M-S, Churchill MJ, Meikle P, Bukrinsky M, Hill AF, Sviridov D (2016) Lipid metabolism in patients infected with Nef-deficient HIV-1 strain, Atherosclerosis, 244: 22-28.

Lener T, Gimona M, Aigner L, Börger V, Buzas E, Camussi G, Chaput N, Chatterjee D, Court FA, Del Portillo HA, O'Driscoll L, Fais S, Falcon-Perez JM, Felderhoff-Mueser U, Fraile L, Gho YS, Görgens A, Gupta RC, Hendrix A, Hermann DM, Hill AF, Hochberg F, Horn PA, de Kleijn D, Kordelas L, Kramer BW, Krämer-Albers EM, Laner-Plamberger S, Laitinen S, Leonardi T, Lorenowicz MJ, Lim SK, Lötvall J, Maguire CA, Marcilla A, Nazarenko I, Ochiya T, Patel T, Pedersen S, Pocsfalvi G, Pluchino S, Quesenberry P, Reischl IG, Rivera FJ, Sanzenbacher R, Schallmoser K, Slaper-Cortenbach I, Strunk D, Tonn T, Vader P, van Balkom BW, Wauben M, Andaloussi SE, Théry C, Rohde E, Giebel B (2015) Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper, Extracell Vesicles, 4:30087.

Polling S, Ormsby AR, Wood RJ, Lee K, Shoubridge C, Hughes JN, Thomas PQ, Griffin MD, Hill AF, Bowden Q, Böcking T, Hatters DM (2015) Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation, Nat Struct Mol Biol., 22(12):1008-15.

Quek C, Hung CH, Lonie A, Bellingham SA, Hill AF (2015) iSRAP – a one-touch research tool for rapid profiling of small RNA-seq data, J Extracell Vesicles, 4: 29454.

De Mario A, Castellani A, Peggion C, Massimino ML, Lim D, Hill AF, Sorgato MC, Bertoli A (2015) The prion protein constitutively controls neuronal store-operated Ca2+ entry through Fyn kinase, Front Cell Neurosci, doi.org/10.3389/fncel.2015.00416.

Lunavat TR, Cheng L, Kim D-K, Bhadury J, Jang SC, Lasser C, Sharples RA, Lopez MD, Nilsson J, Gho YS, Hill AF and Lotvall J (2015) Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells – evidence of unique microRNA cargos, RNA Biol., 12(8): 810-23.

Bellingham SA, Guo BB and Hill AF (2015) The secret life of extracellular vesicles in metal homeostasis and neurodegeneration, Biol Cell, 107(11):389-418.

Sviridov D and Hill AF (2015) Atherosclerosis: cell biology and lipoproteins. Not a day without microRNA, Curr Opin Lipidol., 26(4): 355-56.

Pathan M, Keerthikumar S, Ang C-S, Gangoda L, Quek CYJ, Williamson NA, Mouradov D, Sieber OM, Simpson RJ, Salim A, Bacic A, Hill AF, Stroud DA, Ryan MT, Agbinya JI, Mariadasson JM, Burgess AW and Mathivanan S (2015) FunRich: An open access standalone functional enrichment and interaction network analysis tool, Proteomics, 15(15): 2597-601.

Ellet LJ, Coleman BM, Shambrook M, Johanssen V, Collins SJ, Masters CL, Hill AF and Lawson VA (2015) Glycosaminoglycan sulfation determines the biochemical properties of prion protein aggregates, Glycobiology, 25(7): 745-55.

Coleman BM and Hill AF (2015) Extracellular vesicles – their role in the packaging and spread of misfolded proteins associated with neurodegenerative diseases, Semin Cell Dev Biol., 40:89-96.

Johanssen T, Suphantarida N, Donnelly PS, Liu ZM, Petrou S, Hill AF and Barnham KJ (2015) PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning, Neurobiol Dis., doi: 10.1016/j.nbd.2015.02.008.

Guo BB, Bellingham SA and Hill AF (2015) The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes, J Biol Chem., 290(6): 3455-67.

Iqbal Hossain M, Hoque A, Lessene G, Aizuddin Kamaruddin M, Chu PW, Ng IH, Irtegun S, Ng DC, Bogoyevitch MA, Burgess AW, Hill AF and Cheng HC (2015) Dual role of Src kinase in governing neuronal survival, Brain Res., 1594: 1-14.

Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, Aikawa E, Baj-Krzyworzeka M, van Balkom BW, Belting M, Blanc L, Bond V, Bongiovanni A, Borràs FE, Buée L, Buzás EI, Cheng L, Clayton A, Cocucci E, Dela Cruz CS, Desiderio DM, Di Vizio D, Ekström K, Falcon-Perez JM, Gardiner C, Giebel B, Greening DW, Gross JC, Gupta D, Hendrix A, Hill AF, Hill MM, Nolte-'t Hoen E, Hwang DW, Inal J, Jagannadham MV, Jayachandran M, Jee YK, Jørgensen M, Kim KP, Kim YK, Kislinger T, Lässer C, Lee DS, Lee H, van Leeuwen J, Lener T, Liu ML, Lötvall J, Marcilla A, Mathivanan S, Möller A, Morhayim J, Mullier F, Nazarenko I, Nieuwland R, Nunes DN, Pang K, Park J, Patel T, Pocsfalvi G, Del Portillo H, Putz U, Ramirez MI, Rodrigues ML, Roh TY, Royo F, Sahoo S, Schiffelers R, Sharma S, Siljander P, Simpson RJ, Soekmadji C, Stahl P, Stensballe A, Stępień E, Tahara H, Trummer A, Valadi H, Vella LJ, Wai SN, Witwer K, Yáñez-Mó M, Youn H, Zeidler R and Gho YS (2015) EVpedia: a community web portal for extracellular vesicles research, Bioinformatics, 31(6): 933-39.

Lopes MH, Santos TG, Rodrigues BR, Queiroz-Hazarbassanov N, Cunha IW, Wasilewska-Sampaio AP, Costa-Silva B, Marchi FA, Bleggi-Torres LF, Sanematsu PI, Suzuki SH, Oba-Shinjo SM, Marie SK, Toulmin E, Hill AF and Martins VR (2015) Disruption of prion protein-HOP engagement impairs glioblastoma growth and cognitive decline and improves overall survival, Oncogene, 34(25): 3305-14.

Lötvall J, Hill AF, Hochberg F, Buzás EI, Di Vizio D, Gardiner C, Gho YS, Kurochkin IV, Mathivanan S, Quesenberry P, Sahoo S, Tahara H, Wauben MH, Witwer KW and Théry C (2014) Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles, J Extracell Vesicles, 3: 26913, doi:10.3402/jev.v3.26913.

Cheng L, Doecke JD, Sharples RA, Villemagne VL, Fowler CJ, Rembach A, Martins RN, Rowe CC, Macaulay SL, Masters CL and Hill AF (2014) Prognostic serum miRNA biomarkers associated with Alzheimer's disease shows concordance with neuropsychological and neuroimaging assessment, Mol Psychiatry, 20(10): 1188-96.

Cheng L, Sharples RA, Scicluna B and Hill AF (2014) Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood, J Extracell Vesicles, doi: 10.3402/jev.v3.23743.

Grad LI, Yerbury JJ, Turner BJ, Guest WC, Pokrishevsky E, O'Neill MA, Yanai A, Silverman JM, Zeineddine R, Corcoran L, Kumita JR, Luheshi L, Yousefi M, Coleman BM, Hill AF, Plotkin SS, Mackenzie IR and Cashman NR (2014) Intercellular propagated misfolding of wild-type Cu-Zn superoxide dismutase occurs via exosome-dependent and independent mechanisms, Proc Natl Acad Sci USA, 111(9): 3620-25.

Polling S, Mok YF, Ramdzan YM, Turner BJ, Yerbury JJ, Hill AF and Hatters DM (2014) Misfolded polyglutamine, polyalanine, and superoxide dismutase 1 aggregate via distinct pathways in the cell, J Biol Chem., 289(10): 6669-80.

Coleman BM, Harrison CF, Guo B, Masters CL, Barnham KJ, Lawson VA and Hill AF (2014) Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality, J Virol., 88(5): 2690-703.

Johanssen VA, Johanssen T, Masters CL, Hill AF, Barnham KJ and Collins SJ (2014) C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage, Biochem J., 459(1): 103-15.

Cui HL, Guo B, Scicluna B, Coleman BM, Lawson VA, Ellett L, Meikle PJ, Bukrinsky M, Mukhamedova N, Sviridov D and Hill AF (2014) Prion infection impairs cholesterol metabolism in neuronal cells, J Biol Chem., 289(2):789-802.

Cheng L, Sun X, Scicluna BJ, Coleman BM and Hill AF (2014) Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine, Kidney Int., 86(2): 433-44.

Hill AF, Pegtel DM, Lambertz U, Leonardi T, O'Driscoll L, Pluchino S, Ter-Ovanesyan D and Nolte-'t Hoen EN (2013) ISEV position paper: extracellular vesicle RNA analysis and bioinformatics, J Extracell Vesicles, doi: 10.3402/jev.v2i0.22859.

Hsiao JH, Fu Y, Hill AF, Halliday GM and Kim WS (2013) Elevation in sphingomyelin synthase activity is associated with increases in amyloid-beta peptide generation, PLoS One, 8(8): e74016, doi: 10.1371/journal.pone.0074016..

Bujalka H, Koenning M, Jackson S, Perreau VM, Pope B, Hay CM, Mitew S, Hill AF, Lu QR, Wegner M, Srinivasan R, Svaren J, Willingham M, Barres BA and Emery B (2013) MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes, PLoS Biol., 11(8): e1001625.

Cheng L, Quek CY, Sun X, Bellingham SA and Hill AF (2013) The detection of microRNA associated with Alzheimer's disease in biological fluids using next-generation sequencing technologies, Front Genet., doi: 10.3389/fgene.2013.00150.

Chia PZ, Toh WH, Sharples R, Gasnereau I, Hill AF and Gleeson PA (2013) Intracellular itinerary of internalised β-secretase, BACE1, and its potential impact on β-amyloid peptide biogenesis, Traffic, 14(9): 997-1013.

Regev-Rudzki N, Wilson DW, Carvalho TG, Sisquella X, Coleman BM, Rug M, Bursac D, Angrisano F, Gee M, Hill AF, Baum J and Cowman AF (2013) Cell-cell communication between malaria-infected red blood cells via exosome-like vesicles, Cell, 153(5): 1120-33.

Hossain MI, Roulston CL, Kamaruddin MA, Chu PW, Ng DC, Dusting GJ, Bjorge JD, Williamson NA, Fujita DJ, Cheung SN, Chan TO, Hill AF and Cheng HC (2013) A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity, J Biol Chem., 288(14): 9696-709.

Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL, Shteynberg D, Moritz RL, Zhu HJ and Simpson RJ (2013) Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition, Mol Cell Proteomics, 12(8): 2148-59.

Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, Bond VC, Borràs FE, Breakefield X, Budnik V, Buzas E, Camussi G, Clayton A, Cocucci E, Falcon-Perez JM, Gabrielsson S, Gho YS, Gupta D, Harsha HC, Hendrix A, Hill AF, Inal JM, Jenster G, Krämer-Albers EM, Lim SK, Llorente A, Lötvall J, Marcilla A, Mincheva-Nilsson L, Nazarenko I, Nieuwland R, Nolte-'t Hoen EN, Pandey A, Patel T, Piper MG, Pluchino S, Prasad TS, Rajendran L, Raposo G, Record M, Reid GE, Sánchez-Madrid F, Schiffelers RM, Siljander P, Stensballe A, Stoorvogel W, Taylor D, Thery C, Valadi H, van Balkom BW, Vázquez J, Vidal M, Wauben MH, Yáñez-Mó M, Zoeller M and Mathivanan S (2012) Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation, PLoS Biol., 10(12): e1001450.

Klemm, HMJ, Welton JM, Masters CL, Hill AF, Collins SJ and Lawson VA (2012) The prion protein preference of sporadic Creutzfeldt-Jakob disease subtypes, J Biol Chem., 287(43): 36465-72.

Bellingham SA, Coleman BM and Hill AF (2012) Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion infected neuronal cells, Nucleic Acids Res., 40(21): 10937-49.

Coleman BM, Hanssen E, Lawson VA and Hill AF (2012) Prion infected cells regulate the release of exosomes with distinct ultrastructural features, FASEB Journal, 26(10): 4160-73.

Falsone SF, Meyer NH, Schrank E, Leitinger G, Pham CLL, Fodero-Tavoletti MT, Holmberg M, Nollen EA, Dulle M, Scicluna B, Gesslbauer B, Ruckert HM, Wagner G, Kungl AJ, Hill AF, Cappai R and Zangger K (2012) SERF protein is a direct modifier of amyloid fiber assembly, Cell Rep., 2(2): 358-71.

Tu E, Ang DKY, Bellingham SA, Hogan TV, Teng MWL, Smyth MJ, Hill AF and van Driel IR (2012) Both IFNγ and IL-17 are important for the development of severe autoimmune gastritis, Eur J Immunol.,  42(10): 2574-83.

Bellingham SA, Guo B, Coleman BM and Hill AF (2012) Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? Front Physiol., doi: 10.3389/fphys.2012.00124.

Hill AF, Lawson VA and Collins SJ (2012) Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity, Mol Neurodegener., 7(1):18.

Polling S, Hill AF and Hatters DM (2012) Polyglutamine aggregation in Huntington and related diseases, Adv Exp Med Biol., 769: 125-40.

Karas JA, Boland M, Haigh C, Johanssen VA, Hill AF, Barnham KJ, Collins SJ and Scanlon D (2012) Microwave synthesis of prion protein fragments up to 111 amino acids in length generates biologically active peptides, Int J Pept Res Ther., 18(1): 21-29.

Hung LW, Villemagne VL, Cheng L, Sherratt NA, Ayton S, White AR, Crouch PJ, Lin SC, Leong S, Wilkins S, George J, Roberts B, Pham CL, Chiu FCK, Shackleford DM, Powell AK, Masters CL, Bush AI, O'Keefe GO, Culvenor JG, Cappai R, Cherny RA, Donnelly PS, Hill AF, Finkelstein DI and Barnham KJ (2012) The hypoxia imaging agent, CuII(atsm), is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease, J Exp Med., 209(4): 837-54.

Li H, Evin G, Hill AF, Hung YH, Bush AI and Garner B (2012) Dissociation of ERK signalling inhibition from the anti-amyloidogenic action of synthetic ceramide analogues, Clin Sci (Lond)., 122(9): 409-19.

Houghton FJ, Bellingham SA, Hill AF, Bourges D, Ang DK, Gemetzis T, Gasnereau I and Gleeson PA (2012) Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport, Exp Cell Res., 318(5): 464-77.

Johanssen VA, Barnham KJ, Masters CL, Hill AF and Collins SJ (2012) Generating recombinant C-terminal prion protein fragments of exact native sequence, Neurochem Int., 60(3): 318-26.

Kim WS, Hill AF, Fitzgerald ML, Freeman MW, Evin G and Garner B (2012) Wild type and Tangier disease ABCA1 mutants modulate cellular amyloid-β production independent of cholesterol efflux activity, J Alzheimers Dis., 27(2): 441-52.

Santosa C, Rasche S, Barakat A, Bellingham SA, Ho M, Tan J, Hill AF, Masters CL, McLean C and Evin G (2011) Decreased expression of GGA3 protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein, Neurobiol Dis., 43(1): 176-83.

Masters CL, Kril JJ, Halliday GM, Pamphlett R, Collins S, Hill AF and McLean C (2011) Overview and recent advances in neuropathology. Part 2: neurodegeneration, Pathology, 43(2): 93-102.

Dinet V, An N, Ciccotosto GD, Bruban J, Maoui A, Bellingham SA, Hill AF, Andersen OM, Nykjaer A, Jonet L, Cappai R and Mascarelli F (2011) APP involvement in retinogenesis of mice, Acta Neuropathol., 121(3): 351-63.

Vella LJ, Cappai R and Hill AF (2011) The role of exosomes in the pathogenesis of prion infection, in SJ Collins and VA Lawson, eds., The Cellular and Molecular Biology of Prion Disease, Research Signpost.

Miles LA, Crespi GA, Han S, Hill AF and Parker MW (2011) An Escherichia coli cell-free system for recombinant protein synthesis on a milligram scale, Methods Mol Biol., 752: 17-28.

*Corresponding author.