Publications

For a complete list of publications see:
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Alhuwaider AAH and Dougan DA (2017) AAA+ machines of protein destruction in mycobacteria, Front Mol Biosci., doi.org/10.3389/fmolb.2017.00049.

Dougan DA (2017) Pro(moting) the turnover of gluconeogenic enzymes by a new branch of the N-end rule pathway, Trends Biochem Sci., 42(5): 330-32.

Tan JL, Ward L, Truscott KN and Dougan DA (2016) The N-end rule adaptor protein ClpS from Plasmodium falciparum exhibits broad substrate specificity, FEBS Lett., 590: 3397-406.

Bezawork-Geleta A, Brodie EJ, Dougan DA and Truscott KN (2015) LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins, Sci Rep., 5:17397, doi:10.1038/srep17397.

Micevski D, Zammit JE, Truscott KN and Dougan DA (2015) Anti-adaptors use distinct modes of binding to inhibit the RssB-dependent turnover of RpoS (σ(S)) by ClpXP, Front Mol Biosci., doi: 10.3389/fmolb.2015.00015.

Bezawork-Geleta A, Saiyed T, Dougan DA and Truscott KN (2014) Mitochondrial matrix proteostasis is linked to hereditary paraganglioma: LON-mediated turnover of the human flavinylation factor SDH5 is regulated by its interaction with SDHA, FASEB J., 28(4): 1794-804.

Gur E, Ottofueling R and Dougan DA (2013) Machines of destruction – AAA+ proteases and the adaptors that control them, in Dougan DA, ed., Regulated Proteolysis in Microorganisms: Subcellular Biochemistry, 66: 3-33.

Miceviski D and Dougan DA (2013) Proteolytic regulation of stress response pathways in Escherichia coli, in Dougan DA, ed., Regulated Proteolysis in Microorganisms: Subcellular Biochemistry, 66: 105-28.

Nagpal J, Tan JL, Truscott KN, Heras B and Dougan DA (2013) Control of protein function through regulated protein degradation: biotechnological and biomedical applications, J Mol Microbiol Biotechnol., 23(4-5): 335-44.

Lowth BR, Kirstein-Miles J, Saiyed T, Brötz-Oesterhelt H, Morimoto RI, Truscott KN and Dougan DA (2012) Substrate recognition and processing by a Walker B mutant of the human mitochondrial AAA+ protein CLPX, J Struct Biol.,179(2): 193-201.

Dougan DA, Micevski D and Truscott KN (2012) The N-end rule pathway: from recognition by N-recognins, to destruction by AAA+ proteases, BBA Mol Cell Res., 1823(1): 83-91.

Dougan DA (2011) Chemical activators of ClpP: turning Jekyll into Hyde, Chem Biol., 18(9): 1072-74.

Truscott KN, Bezawork-Geleta A and Dougan DA (2011) Unfolded protein responses in bacteria and mitochondria: a central role for the ClpXP machine, IUBMB Life, 63(11): 955-63.